Immunomodulatory effect of camellia oil (Camellia oleifera Abel.) on CD19+ B cells enrichment and IL-10 production in BALB/c mice

Camellia oil (Camellia oleifera Abel.) has anti-inflammatory, antioxidant, and microbiota-modulating abilities, but little is known about the effects of camellia oil on immune cell immunomodulation. This study aimed to evaluate the immunomodulatory ability of camellia oil. Firstly, oleic acid (77.98...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Chia-Ying Lin, Sheng-Yi Chen, Wei-Ting Lee, Gow-Chin Yen
Formato:	article
Lenguaje:	EN
Publicado:	Elsevier 2022
Materias:	Camellia oil Macrophage Cytokine B cell Immunomodulation Nutrition. Foods and food supply TX341-641
Acceso en línea:	https://doaj.org/article/0bdffee836ea4a3fb685c1e264d47a3a
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:0bdffee836ea4a3fb685c1e264d47a3a
record_format	dspace
spelling	oai:doaj.org-article:0bdffee836ea4a3fb685c1e264d47a3a2021-12-02T05:00:14ZImmunomodulatory effect of camellia oil (Camellia oleifera Abel.) on CD19+ B cells enrichment and IL-10 production in BALB/c mice1756-464610.1016/j.jff.2021.104863https://doaj.org/article/0bdffee836ea4a3fb685c1e264d47a3a2022-01-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S1756464621005120https://doaj.org/toc/1756-4646Camellia oil (Camellia oleifera Abel.) has anti-inflammatory, antioxidant, and microbiota-modulating abilities, but little is known about the effects of camellia oil on immune cell immunomodulation. This study aimed to evaluate the immunomodulatory ability of camellia oil. Firstly, oleic acid (77.98%) rich and antioxidant characteristics were found in camellia oil. Besides, camellia oil significantly increased phagocytosis in RAW 264.7 macrophages and primary peritoneal macrophages, respectively. Nitric oxide (NO) production was reduced in camellia oil-treated RAW 264.7 cells and BALB/c mice. Additionally, interleukin-10 (IL-10) was significantly induced by camellia oil treatment in primary splenocytes. Interestingly, IL-10-producing splenic macrophages have been demonstrated to promote B cell proliferation. Noteworthily, this study provided compelling evidence that administration of camellia oil significantly enriched the cluster of differentiation 19 positive (CD19+) B cell population in BALB/c mice. In conclusion, the data demonstrated that oleic acid-rich camellia oil may significantly induce the CD19+ humoral immune response.Chia-Ying LinSheng-Yi ChenWei-Ting LeeGow-Chin YenElsevierarticleCamellia oilMacrophageCytokineB cellImmunomodulationNutrition. Foods and food supplyTX341-641ENJournal of Functional Foods, Vol 88, Iss , Pp 104863- (2022)
institution	DOAJ
collection	DOAJ
language	EN
topic	Camellia oil Macrophage Cytokine B cell Immunomodulation Nutrition. Foods and food supply TX341-641
spellingShingle	Camellia oil Macrophage Cytokine B cell Immunomodulation Nutrition. Foods and food supply TX341-641 Chia-Ying Lin Sheng-Yi Chen Wei-Ting Lee Gow-Chin Yen Immunomodulatory effect of camellia oil (Camellia oleifera Abel.) on CD19+ B cells enrichment and IL-10 production in BALB/c mice
description	Camellia oil (Camellia oleifera Abel.) has anti-inflammatory, antioxidant, and microbiota-modulating abilities, but little is known about the effects of camellia oil on immune cell immunomodulation. This study aimed to evaluate the immunomodulatory ability of camellia oil. Firstly, oleic acid (77.98%) rich and antioxidant characteristics were found in camellia oil. Besides, camellia oil significantly increased phagocytosis in RAW 264.7 macrophages and primary peritoneal macrophages, respectively. Nitric oxide (NO) production was reduced in camellia oil-treated RAW 264.7 cells and BALB/c mice. Additionally, interleukin-10 (IL-10) was significantly induced by camellia oil treatment in primary splenocytes. Interestingly, IL-10-producing splenic macrophages have been demonstrated to promote B cell proliferation. Noteworthily, this study provided compelling evidence that administration of camellia oil significantly enriched the cluster of differentiation 19 positive (CD19+) B cell population in BALB/c mice. In conclusion, the data demonstrated that oleic acid-rich camellia oil may significantly induce the CD19+ humoral immune response.
format	article
author	Chia-Ying Lin Sheng-Yi Chen Wei-Ting Lee Gow-Chin Yen
author_facet	Chia-Ying Lin Sheng-Yi Chen Wei-Ting Lee Gow-Chin Yen
author_sort	Chia-Ying Lin
title	Immunomodulatory effect of camellia oil (Camellia oleifera Abel.) on CD19+ B cells enrichment and IL-10 production in BALB/c mice
title_short	Immunomodulatory effect of camellia oil (Camellia oleifera Abel.) on CD19+ B cells enrichment and IL-10 production in BALB/c mice
title_full	Immunomodulatory effect of camellia oil (Camellia oleifera Abel.) on CD19+ B cells enrichment and IL-10 production in BALB/c mice
title_fullStr	Immunomodulatory effect of camellia oil (Camellia oleifera Abel.) on CD19+ B cells enrichment and IL-10 production in BALB/c mice
title_full_unstemmed	Immunomodulatory effect of camellia oil (Camellia oleifera Abel.) on CD19+ B cells enrichment and IL-10 production in BALB/c mice
title_sort	immunomodulatory effect of camellia oil (camellia oleifera abel.) on cd19+ b cells enrichment and il-10 production in balb/c mice
publisher	Elsevier
publishDate	2022
url	https://doaj.org/article/0bdffee836ea4a3fb685c1e264d47a3a
work_keys_str_mv	AT chiayinglin immunomodulatoryeffectofcamelliaoilcamelliaoleiferaabeloncd19bcellsenrichmentandil10productioninbalbcmice AT shengyichen immunomodulatoryeffectofcamelliaoilcamelliaoleiferaabeloncd19bcellsenrichmentandil10productioninbalbcmice AT weitinglee immunomodulatoryeffectofcamelliaoilcamelliaoleiferaabeloncd19bcellsenrichmentandil10productioninbalbcmice AT gowchinyen immunomodulatoryeffectofcamelliaoilcamelliaoleiferaabeloncd19bcellsenrichmentandil10productioninbalbcmice
_version_	1718400812134170624

Immunomodulatory effect of camellia oil (Camellia oleifera Abel.) on CD19+ B cells enrichment and IL-10 production in BALB/c mice

Ejemplares similares