Architectural control of metabolic plasticity in epithelial cancer cells

To understand the role of architectural environment on metabolic plasticity of cancer cells, Al Masri et al. compare the metabolic activities of cancer cells grown in 2D vs 3D. They find that cells cultivated in 2D are highly glycolytic and dependent on glucose and glutamine for growth, while cells...

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Autores principales: Maia Al-Masri, Karina Paliotti, Raymond Tran, Ruba Halaoui, Virginie Lelarge, Sudipa Chatterjee, Li-Ting Wang, Christopher Moraes, Luke McCaffrey
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/0be89b27d5bc4496a6aa395fe7556199
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