Establishment and characterization of new tumor xenografts and cancer cell lines from EBV-positive nasopharyngeal carcinoma

Establishment and characterization of new tumor xenografts and cancer cell lines from EBV-positive nasopharyngeal carcinoma

The lack of appropriate models restricts pre-clinical research for nasopharyngeal carcinoma (NPC). Here the authors report the development and characterization of NPC patient-derived xenografts (PDXs), and EBV positive NPC cell line from patient tumor, and suggest their potential use in future NPC r...

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Autores principales: Weitao Lin, Yim Ling Yip, Lin Jia, Wen Deng, Hong Zheng, Wei Dai, Josephine Mun Yee Ko, Kwok Wai Lo, Grace Tin Yun Chung, Kevin Y. Yip, Sau-Dan Lee, Johnny Sheung-Him Kwan, Jun Zhang, Tengfei Liu, Jimmy Yu-Wai Chan, Dora Lai-Wan Kwong, Victor Ho-Fun Lee, John Malcolm Nicholls, Pierre Busson, Xuefeng Liu, Alan Kwok Shing Chiang, Kwai Fung Hui, Hin Kwok, Siu Tim Cheung, Yuk Chun Cheung, Chi Keung Chan, Bin Li, Annie Lai-Man Cheung, Pok Man Hau, Yuan Zhou, Chi Man Tsang, Jaap Middeldorp, Honglin Chen, Maria Li Lung, Sai Wah Tsao
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/0bf1deca4e9646d1b93328014cc28ef0
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spelling oai:doaj.org-article:0bf1deca4e9646d1b93328014cc28ef02021-12-02T15:34:00ZEstablishment and characterization of new tumor xenografts and cancer cell lines from EBV-positive nasopharyngeal carcinoma10.1038/s41467-018-06889-52041-1723https://doaj.org/article/0bf1deca4e9646d1b93328014cc28ef02018-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06889-5https://doaj.org/toc/2041-1723The lack of appropriate models restricts pre-clinical research for nasopharyngeal carcinoma (NPC). Here the authors report the development and characterization of NPC patient-derived xenografts (PDXs), and EBV positive NPC cell line from patient tumor, and suggest their potential use in future NPC research.Weitao LinYim Ling YipLin JiaWen DengHong ZhengWei DaiJosephine Mun Yee KoKwok Wai LoGrace Tin Yun ChungKevin Y. YipSau-Dan LeeJohnny Sheung-Him KwanJun ZhangTengfei LiuJimmy Yu-Wai ChanDora Lai-Wan KwongVictor Ho-Fun LeeJohn Malcolm NichollsPierre BussonXuefeng LiuAlan Kwok Shing ChiangKwai Fung HuiHin KwokSiu Tim CheungYuk Chun CheungChi Keung ChanBin LiAnnie Lai-Man CheungPok Man HauYuan ZhouChi Man TsangJaap MiddeldorpHonglin ChenMaria Li LungSai Wah TsaoNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Weitao Lin
Yim Ling Yip
Lin Jia
Wen Deng
Hong Zheng
Wei Dai
Josephine Mun Yee Ko
Kwok Wai Lo
Grace Tin Yun Chung
Kevin Y. Yip
Sau-Dan Lee
Johnny Sheung-Him Kwan
Jun Zhang
Tengfei Liu
Jimmy Yu-Wai Chan
Dora Lai-Wan Kwong
Victor Ho-Fun Lee
John Malcolm Nicholls
Pierre Busson
Xuefeng Liu
Alan Kwok Shing Chiang
Kwai Fung Hui
Hin Kwok
Siu Tim Cheung
Yuk Chun Cheung
Chi Keung Chan
Bin Li
Annie Lai-Man Cheung
Pok Man Hau
Yuan Zhou
Chi Man Tsang
Jaap Middeldorp
Honglin Chen
Maria Li Lung
Sai Wah Tsao
Establishment and characterization of new tumor xenografts and cancer cell lines from EBV-positive nasopharyngeal carcinoma
description The lack of appropriate models restricts pre-clinical research for nasopharyngeal carcinoma (NPC). Here the authors report the development and characterization of NPC patient-derived xenografts (PDXs), and EBV positive NPC cell line from patient tumor, and suggest their potential use in future NPC research.
format article
author Weitao Lin
Yim Ling Yip
Lin Jia
Wen Deng
Hong Zheng
Wei Dai
Josephine Mun Yee Ko
Kwok Wai Lo
Grace Tin Yun Chung
Kevin Y. Yip
Sau-Dan Lee
Johnny Sheung-Him Kwan
Jun Zhang
Tengfei Liu
Jimmy Yu-Wai Chan
Dora Lai-Wan Kwong
Victor Ho-Fun Lee
John Malcolm Nicholls
Pierre Busson
Xuefeng Liu
Alan Kwok Shing Chiang
Kwai Fung Hui
Hin Kwok
Siu Tim Cheung
Yuk Chun Cheung
Chi Keung Chan
Bin Li
Annie Lai-Man Cheung
Pok Man Hau
Yuan Zhou
Chi Man Tsang
Jaap Middeldorp
Honglin Chen
Maria Li Lung
Sai Wah Tsao
author_facet Weitao Lin
Yim Ling Yip
Lin Jia
Wen Deng
Hong Zheng
Wei Dai
Josephine Mun Yee Ko
Kwok Wai Lo
Grace Tin Yun Chung
Kevin Y. Yip
Sau-Dan Lee
Johnny Sheung-Him Kwan
Jun Zhang
Tengfei Liu
Jimmy Yu-Wai Chan
Dora Lai-Wan Kwong
Victor Ho-Fun Lee
John Malcolm Nicholls
Pierre Busson
Xuefeng Liu
Alan Kwok Shing Chiang
Kwai Fung Hui
Hin Kwok
Siu Tim Cheung
Yuk Chun Cheung
Chi Keung Chan
Bin Li
Annie Lai-Man Cheung
Pok Man Hau
Yuan Zhou
Chi Man Tsang
Jaap Middeldorp
Honglin Chen
Maria Li Lung
Sai Wah Tsao
author_sort Weitao Lin
title Establishment and characterization of new tumor xenografts and cancer cell lines from EBV-positive nasopharyngeal carcinoma
title_short Establishment and characterization of new tumor xenografts and cancer cell lines from EBV-positive nasopharyngeal carcinoma
title_full Establishment and characterization of new tumor xenografts and cancer cell lines from EBV-positive nasopharyngeal carcinoma
title_fullStr Establishment and characterization of new tumor xenografts and cancer cell lines from EBV-positive nasopharyngeal carcinoma
title_full_unstemmed Establishment and characterization of new tumor xenografts and cancer cell lines from EBV-positive nasopharyngeal carcinoma
title_sort establishment and characterization of new tumor xenografts and cancer cell lines from ebv-positive nasopharyngeal carcinoma
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/0bf1deca4e9646d1b93328014cc28ef0
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