The chromatin remodeler RSF1 controls centromeric histone modifications to coordinate chromosome segregation

The chromatin remodeler RSF1 is enriched at mitotic centromeres but its function there is poorly understood. Here, the authors show that RSF1 regulates H2A phosphorylation and acetylation at mitotic centromeres and contributes to chromosome stability.

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Autores principales: Ho-Soo Lee, Zhonghui Lin, Sunyoung Chae, Young-Suk Yoo, Byung-Gyu Kim, Youngsoo Lee, Jared L. Johnson, You-Sun Kim, Lewis C. Cantley, Chang-Woo Lee, Hongtao Yu, Hyeseong Cho
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Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/0bf89570019f4e5fb76ec6c3b0d31610
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spelling oai:doaj.org-article:0bf89570019f4e5fb76ec6c3b0d316102021-12-02T14:40:06ZThe chromatin remodeler RSF1 controls centromeric histone modifications to coordinate chromosome segregation10.1038/s41467-018-06377-w2041-1723https://doaj.org/article/0bf89570019f4e5fb76ec6c3b0d316102018-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06377-whttps://doaj.org/toc/2041-1723The chromatin remodeler RSF1 is enriched at mitotic centromeres but its function there is poorly understood. Here, the authors show that RSF1 regulates H2A phosphorylation and acetylation at mitotic centromeres and contributes to chromosome stability.Ho-Soo LeeZhonghui LinSunyoung ChaeYoung-Suk YooByung-Gyu KimYoungsoo LeeJared L. JohnsonYou-Sun KimLewis C. CantleyChang-Woo LeeHongtao YuHyeseong ChoNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Ho-Soo Lee
Zhonghui Lin
Sunyoung Chae
Young-Suk Yoo
Byung-Gyu Kim
Youngsoo Lee
Jared L. Johnson
You-Sun Kim
Lewis C. Cantley
Chang-Woo Lee
Hongtao Yu
Hyeseong Cho
The chromatin remodeler RSF1 controls centromeric histone modifications to coordinate chromosome segregation
description The chromatin remodeler RSF1 is enriched at mitotic centromeres but its function there is poorly understood. Here, the authors show that RSF1 regulates H2A phosphorylation and acetylation at mitotic centromeres and contributes to chromosome stability.
format article
author Ho-Soo Lee
Zhonghui Lin
Sunyoung Chae
Young-Suk Yoo
Byung-Gyu Kim
Youngsoo Lee
Jared L. Johnson
You-Sun Kim
Lewis C. Cantley
Chang-Woo Lee
Hongtao Yu
Hyeseong Cho
author_facet Ho-Soo Lee
Zhonghui Lin
Sunyoung Chae
Young-Suk Yoo
Byung-Gyu Kim
Youngsoo Lee
Jared L. Johnson
You-Sun Kim
Lewis C. Cantley
Chang-Woo Lee
Hongtao Yu
Hyeseong Cho
author_sort Ho-Soo Lee
title The chromatin remodeler RSF1 controls centromeric histone modifications to coordinate chromosome segregation
title_short The chromatin remodeler RSF1 controls centromeric histone modifications to coordinate chromosome segregation
title_full The chromatin remodeler RSF1 controls centromeric histone modifications to coordinate chromosome segregation
title_fullStr The chromatin remodeler RSF1 controls centromeric histone modifications to coordinate chromosome segregation
title_full_unstemmed The chromatin remodeler RSF1 controls centromeric histone modifications to coordinate chromosome segregation
title_sort chromatin remodeler rsf1 controls centromeric histone modifications to coordinate chromosome segregation
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/0bf89570019f4e5fb76ec6c3b0d31610
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