Glutamic acid is a carrier for hydrazine during the biosyntheses of fosfazinomycin and kinamycin

The natural products fosfazinomycin A and kinamycin D are structurally distinct except for a nitrogen-nitrogen (N-N) bond. Here, the authors show that fosfazinomycin and kinamycin share a common pathway for N-N bond formation that is different from pathways found for other natural products.

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Autores principales:	Kwo-Kwang A. Wang, Tai L. Ng, Peng Wang, Zedu Huang, Emily P. Balskus, Wilfred A. van der Donk
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/0bfcbb1345f341b6b1521cc37c83a8a0
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spelling	oai:doaj.org-article:0bfcbb1345f341b6b1521cc37c83a8a02021-12-02T14:39:26ZGlutamic acid is a carrier for hydrazine during the biosyntheses of fosfazinomycin and kinamycin10.1038/s41467-018-06083-72041-1723https://doaj.org/article/0bfcbb1345f341b6b1521cc37c83a8a02018-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06083-7https://doaj.org/toc/2041-1723The natural products fosfazinomycin A and kinamycin D are structurally distinct except for a nitrogen-nitrogen (N-N) bond. Here, the authors show that fosfazinomycin and kinamycin share a common pathway for N-N bond formation that is different from pathways found for other natural products.Kwo-Kwang A. WangTai L. NgPeng WangZedu HuangEmily P. BalskusWilfred A. van der DonkNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Kwo-Kwang A. Wang Tai L. Ng Peng Wang Zedu Huang Emily P. Balskus Wilfred A. van der Donk Glutamic acid is a carrier for hydrazine during the biosyntheses of fosfazinomycin and kinamycin
description	The natural products fosfazinomycin A and kinamycin D are structurally distinct except for a nitrogen-nitrogen (N-N) bond. Here, the authors show that fosfazinomycin and kinamycin share a common pathway for N-N bond formation that is different from pathways found for other natural products.
format	article
author	Kwo-Kwang A. Wang Tai L. Ng Peng Wang Zedu Huang Emily P. Balskus Wilfred A. van der Donk
author_facet	Kwo-Kwang A. Wang Tai L. Ng Peng Wang Zedu Huang Emily P. Balskus Wilfred A. van der Donk
author_sort	Kwo-Kwang A. Wang
title	Glutamic acid is a carrier for hydrazine during the biosyntheses of fosfazinomycin and kinamycin
title_short	Glutamic acid is a carrier for hydrazine during the biosyntheses of fosfazinomycin and kinamycin
title_full	Glutamic acid is a carrier for hydrazine during the biosyntheses of fosfazinomycin and kinamycin
title_fullStr	Glutamic acid is a carrier for hydrazine during the biosyntheses of fosfazinomycin and kinamycin
title_full_unstemmed	Glutamic acid is a carrier for hydrazine during the biosyntheses of fosfazinomycin and kinamycin
title_sort	glutamic acid is a carrier for hydrazine during the biosyntheses of fosfazinomycin and kinamycin
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/0bfcbb1345f341b6b1521cc37c83a8a0
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Glutamic acid is a carrier for hydrazine during the biosyntheses of fosfazinomycin and kinamycin

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