Bovine Meat and Milk Factors (BMMFs): Their Proposed Role in Common Human Cancers and Type 2 Diabetes Mellitus
Exemplified by infections with bovine meat and milk factors (BMMFs), this manuscript emphasizes the different mechanistic aspects of infectious agents contributing to human cancers by “direct” or “indirect” interactions. The epidemiology of cancers linked to direct carcinogens (e.g., response to imm...
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2021
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oai:doaj.org-article:0bfd439c2c1c4515a98cbe0e2944fc922021-11-11T15:30:29ZBovine Meat and Milk Factors (BMMFs): Their Proposed Role in Common Human Cancers and Type 2 Diabetes Mellitus10.3390/cancers132154072072-6694https://doaj.org/article/0bfd439c2c1c4515a98cbe0e2944fc922021-10-01T00:00:00Zhttps://www.mdpi.com/2072-6694/13/21/5407https://doaj.org/toc/2072-6694Exemplified by infections with bovine meat and milk factors (BMMFs), this manuscript emphasizes the different mechanistic aspects of infectious agents contributing to human cancers by “direct” or “indirect” interactions. The epidemiology of cancers linked to direct carcinogens (e.g., response to immunosuppression) differs from those cancers linked with indirect infectious interactions. Cancers induced by direct infectious carcinogens commonly increase under immunosuppression, whereas the cancer risk by indirect carcinogens is reduced. This influences their responses to preventive and therapeutic interferences. In addition, we discuss their role in colon, breast and prostate cancers and type II diabetes mellitus. A brief discussion covers the potential role of BMMF infections in acute myeloid leukemia.Ethel-Michele de VilliersHarald zur HausenMDPI AGarticleindirect carcinogenesisbovine meat and milk factors (BMMF)chronic zoonosisNeoplasms. Tumors. Oncology. Including cancer and carcinogensRC254-282ENCancers, Vol 13, Iss 5407, p 5407 (2021) |
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indirect carcinogenesis bovine meat and milk factors (BMMF) chronic zoonosis Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282 |
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indirect carcinogenesis bovine meat and milk factors (BMMF) chronic zoonosis Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282 Ethel-Michele de Villiers Harald zur Hausen Bovine Meat and Milk Factors (BMMFs): Their Proposed Role in Common Human Cancers and Type 2 Diabetes Mellitus |
description |
Exemplified by infections with bovine meat and milk factors (BMMFs), this manuscript emphasizes the different mechanistic aspects of infectious agents contributing to human cancers by “direct” or “indirect” interactions. The epidemiology of cancers linked to direct carcinogens (e.g., response to immunosuppression) differs from those cancers linked with indirect infectious interactions. Cancers induced by direct infectious carcinogens commonly increase under immunosuppression, whereas the cancer risk by indirect carcinogens is reduced. This influences their responses to preventive and therapeutic interferences. In addition, we discuss their role in colon, breast and prostate cancers and type II diabetes mellitus. A brief discussion covers the potential role of BMMF infections in acute myeloid leukemia. |
format |
article |
author |
Ethel-Michele de Villiers Harald zur Hausen |
author_facet |
Ethel-Michele de Villiers Harald zur Hausen |
author_sort |
Ethel-Michele de Villiers |
title |
Bovine Meat and Milk Factors (BMMFs): Their Proposed Role in Common Human Cancers and Type 2 Diabetes Mellitus |
title_short |
Bovine Meat and Milk Factors (BMMFs): Their Proposed Role in Common Human Cancers and Type 2 Diabetes Mellitus |
title_full |
Bovine Meat and Milk Factors (BMMFs): Their Proposed Role in Common Human Cancers and Type 2 Diabetes Mellitus |
title_fullStr |
Bovine Meat and Milk Factors (BMMFs): Their Proposed Role in Common Human Cancers and Type 2 Diabetes Mellitus |
title_full_unstemmed |
Bovine Meat and Milk Factors (BMMFs): Their Proposed Role in Common Human Cancers and Type 2 Diabetes Mellitus |
title_sort |
bovine meat and milk factors (bmmfs): their proposed role in common human cancers and type 2 diabetes mellitus |
publisher |
MDPI AG |
publishDate |
2021 |
url |
https://doaj.org/article/0bfd439c2c1c4515a98cbe0e2944fc92 |
work_keys_str_mv |
AT ethelmicheledevilliers bovinemeatandmilkfactorsbmmfstheirproposedroleincommonhumancancersandtype2diabetesmellitus AT haraldzurhausen bovinemeatandmilkfactorsbmmfstheirproposedroleincommonhumancancersandtype2diabetesmellitus |
_version_ |
1718435223894491136 |