Bovine Meat and Milk Factors (BMMFs): Their Proposed Role in Common Human Cancers and Type 2 Diabetes Mellitus

Exemplified by infections with bovine meat and milk factors (BMMFs), this manuscript emphasizes the different mechanistic aspects of infectious agents contributing to human cancers by “direct” or “indirect” interactions. The epidemiology of cancers linked to direct carcinogens (e.g., response to imm...

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Autores principales: Ethel-Michele de Villiers, Harald zur Hausen
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Lenguaje:EN
Publicado: MDPI AG 2021
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Acceso en línea:https://doaj.org/article/0bfd439c2c1c4515a98cbe0e2944fc92
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spelling oai:doaj.org-article:0bfd439c2c1c4515a98cbe0e2944fc922021-11-11T15:30:29ZBovine Meat and Milk Factors (BMMFs): Their Proposed Role in Common Human Cancers and Type 2 Diabetes Mellitus10.3390/cancers132154072072-6694https://doaj.org/article/0bfd439c2c1c4515a98cbe0e2944fc922021-10-01T00:00:00Zhttps://www.mdpi.com/2072-6694/13/21/5407https://doaj.org/toc/2072-6694Exemplified by infections with bovine meat and milk factors (BMMFs), this manuscript emphasizes the different mechanistic aspects of infectious agents contributing to human cancers by “direct” or “indirect” interactions. The epidemiology of cancers linked to direct carcinogens (e.g., response to immunosuppression) differs from those cancers linked with indirect infectious interactions. Cancers induced by direct infectious carcinogens commonly increase under immunosuppression, whereas the cancer risk by indirect carcinogens is reduced. This influences their responses to preventive and therapeutic interferences. In addition, we discuss their role in colon, breast and prostate cancers and type II diabetes mellitus. A brief discussion covers the potential role of BMMF infections in acute myeloid leukemia.Ethel-Michele de VilliersHarald zur HausenMDPI AGarticleindirect carcinogenesisbovine meat and milk factors (BMMF)chronic zoonosisNeoplasms. Tumors. Oncology. Including cancer and carcinogensRC254-282ENCancers, Vol 13, Iss 5407, p 5407 (2021)
institution DOAJ
collection DOAJ
language EN
topic indirect carcinogenesis
bovine meat and milk factors (BMMF)
chronic zoonosis
Neoplasms. Tumors. Oncology. Including cancer and carcinogens
RC254-282
spellingShingle indirect carcinogenesis
bovine meat and milk factors (BMMF)
chronic zoonosis
Neoplasms. Tumors. Oncology. Including cancer and carcinogens
RC254-282
Ethel-Michele de Villiers
Harald zur Hausen
Bovine Meat and Milk Factors (BMMFs): Their Proposed Role in Common Human Cancers and Type 2 Diabetes Mellitus
description Exemplified by infections with bovine meat and milk factors (BMMFs), this manuscript emphasizes the different mechanistic aspects of infectious agents contributing to human cancers by “direct” or “indirect” interactions. The epidemiology of cancers linked to direct carcinogens (e.g., response to immunosuppression) differs from those cancers linked with indirect infectious interactions. Cancers induced by direct infectious carcinogens commonly increase under immunosuppression, whereas the cancer risk by indirect carcinogens is reduced. This influences their responses to preventive and therapeutic interferences. In addition, we discuss their role in colon, breast and prostate cancers and type II diabetes mellitus. A brief discussion covers the potential role of BMMF infections in acute myeloid leukemia.
format article
author Ethel-Michele de Villiers
Harald zur Hausen
author_facet Ethel-Michele de Villiers
Harald zur Hausen
author_sort Ethel-Michele de Villiers
title Bovine Meat and Milk Factors (BMMFs): Their Proposed Role in Common Human Cancers and Type 2 Diabetes Mellitus
title_short Bovine Meat and Milk Factors (BMMFs): Their Proposed Role in Common Human Cancers and Type 2 Diabetes Mellitus
title_full Bovine Meat and Milk Factors (BMMFs): Their Proposed Role in Common Human Cancers and Type 2 Diabetes Mellitus
title_fullStr Bovine Meat and Milk Factors (BMMFs): Their Proposed Role in Common Human Cancers and Type 2 Diabetes Mellitus
title_full_unstemmed Bovine Meat and Milk Factors (BMMFs): Their Proposed Role in Common Human Cancers and Type 2 Diabetes Mellitus
title_sort bovine meat and milk factors (bmmfs): their proposed role in common human cancers and type 2 diabetes mellitus
publisher MDPI AG
publishDate 2021
url https://doaj.org/article/0bfd439c2c1c4515a98cbe0e2944fc92
work_keys_str_mv AT ethelmicheledevilliers bovinemeatandmilkfactorsbmmfstheirproposedroleincommonhumancancersandtype2diabetesmellitus
AT haraldzurhausen bovinemeatandmilkfactorsbmmfstheirproposedroleincommonhumancancersandtype2diabetesmellitus
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