Quantitative and multiplexed chemical-genetic phenotyping in mammalian cells with QMAP-Seq

Identifying chemical-genetic interactions in mammalian cells is limited to low-throughput or computational methods. Here, the authors present QMAP-Seq, a broadly accessible and scalable approach that uses NGS for pooled high-throughput chemical-genetic profiling in mammalian cells.

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Autores principales:	Sonia Brockway, Geng Wang, Jasen M. Jackson, David R. Amici, Seesha R. Takagishi, Matthew R. Clutter, Elizabeth T. Bartom, Marc L. Mendillo
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/0bffba70303d49d6bfb6d4bae9916ae3
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spelling	oai:doaj.org-article:0bffba70303d49d6bfb6d4bae9916ae32021-12-02T16:56:51ZQuantitative and multiplexed chemical-genetic phenotyping in mammalian cells with QMAP-Seq10.1038/s41467-020-19553-82041-1723https://doaj.org/article/0bffba70303d49d6bfb6d4bae9916ae32020-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-19553-8https://doaj.org/toc/2041-1723Identifying chemical-genetic interactions in mammalian cells is limited to low-throughput or computational methods. Here, the authors present QMAP-Seq, a broadly accessible and scalable approach that uses NGS for pooled high-throughput chemical-genetic profiling in mammalian cells.Sonia BrockwayGeng WangJasen M. JacksonDavid R. AmiciSeesha R. TakagishiMatthew R. ClutterElizabeth T. BartomMarc L. MendilloNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Sonia Brockway Geng Wang Jasen M. Jackson David R. Amici Seesha R. Takagishi Matthew R. Clutter Elizabeth T. Bartom Marc L. Mendillo Quantitative and multiplexed chemical-genetic phenotyping in mammalian cells with QMAP-Seq
description	Identifying chemical-genetic interactions in mammalian cells is limited to low-throughput or computational methods. Here, the authors present QMAP-Seq, a broadly accessible and scalable approach that uses NGS for pooled high-throughput chemical-genetic profiling in mammalian cells.
format	article
author	Sonia Brockway Geng Wang Jasen M. Jackson David R. Amici Seesha R. Takagishi Matthew R. Clutter Elizabeth T. Bartom Marc L. Mendillo
author_facet	Sonia Brockway Geng Wang Jasen M. Jackson David R. Amici Seesha R. Takagishi Matthew R. Clutter Elizabeth T. Bartom Marc L. Mendillo
author_sort	Sonia Brockway
title	Quantitative and multiplexed chemical-genetic phenotyping in mammalian cells with QMAP-Seq
title_short	Quantitative and multiplexed chemical-genetic phenotyping in mammalian cells with QMAP-Seq
title_full	Quantitative and multiplexed chemical-genetic phenotyping in mammalian cells with QMAP-Seq
title_fullStr	Quantitative and multiplexed chemical-genetic phenotyping in mammalian cells with QMAP-Seq
title_full_unstemmed	Quantitative and multiplexed chemical-genetic phenotyping in mammalian cells with QMAP-Seq
title_sort	quantitative and multiplexed chemical-genetic phenotyping in mammalian cells with qmap-seq
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/0bffba70303d49d6bfb6d4bae9916ae3
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Quantitative and multiplexed chemical-genetic phenotyping in mammalian cells with QMAP-Seq

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