Simulating multiple faceted variability in single cell RNA sequencing

Simulated single cell RNA sequencing data is useful for method development and comparison. Here, the authors developed SymSim, a simulator that explicitly models the main factors of variation in single cell data.

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Autores principales: Xiuwei Zhang, Chenling Xu, Nir Yosef
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/0c024b34635d400b80a0b8fd1ba5c64c
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spelling oai:doaj.org-article:0c024b34635d400b80a0b8fd1ba5c64c2021-12-02T17:32:10ZSimulating multiple faceted variability in single cell RNA sequencing10.1038/s41467-019-10500-w2041-1723https://doaj.org/article/0c024b34635d400b80a0b8fd1ba5c64c2019-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-10500-whttps://doaj.org/toc/2041-1723Simulated single cell RNA sequencing data is useful for method development and comparison. Here, the authors developed SymSim, a simulator that explicitly models the main factors of variation in single cell data.Xiuwei ZhangChenling XuNir YosefNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Xiuwei Zhang
Chenling Xu
Nir Yosef
Simulating multiple faceted variability in single cell RNA sequencing
description Simulated single cell RNA sequencing data is useful for method development and comparison. Here, the authors developed SymSim, a simulator that explicitly models the main factors of variation in single cell data.
format article
author Xiuwei Zhang
Chenling Xu
Nir Yosef
author_facet Xiuwei Zhang
Chenling Xu
Nir Yosef
author_sort Xiuwei Zhang
title Simulating multiple faceted variability in single cell RNA sequencing
title_short Simulating multiple faceted variability in single cell RNA sequencing
title_full Simulating multiple faceted variability in single cell RNA sequencing
title_fullStr Simulating multiple faceted variability in single cell RNA sequencing
title_full_unstemmed Simulating multiple faceted variability in single cell RNA sequencing
title_sort simulating multiple faceted variability in single cell rna sequencing
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/0c024b34635d400b80a0b8fd1ba5c64c
work_keys_str_mv AT xiuweizhang simulatingmultiplefacetedvariabilityinsinglecellrnasequencing
AT chenlingxu simulatingmultiplefacetedvariabilityinsinglecellrnasequencing
AT niryosef simulatingmultiplefacetedvariabilityinsinglecellrnasequencing
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