Simulating multiple faceted variability in single cell RNA sequencing
Simulated single cell RNA sequencing data is useful for method development and comparison. Here, the authors developed SymSim, a simulator that explicitly models the main factors of variation in single cell data.
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Nature Portfolio
2019
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oai:doaj.org-article:0c024b34635d400b80a0b8fd1ba5c64c2021-12-02T17:32:10ZSimulating multiple faceted variability in single cell RNA sequencing10.1038/s41467-019-10500-w2041-1723https://doaj.org/article/0c024b34635d400b80a0b8fd1ba5c64c2019-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-10500-whttps://doaj.org/toc/2041-1723Simulated single cell RNA sequencing data is useful for method development and comparison. Here, the authors developed SymSim, a simulator that explicitly models the main factors of variation in single cell data.Xiuwei ZhangChenling XuNir YosefNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-16 (2019) |
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Science Q Xiuwei Zhang Chenling Xu Nir Yosef Simulating multiple faceted variability in single cell RNA sequencing |
description |
Simulated single cell RNA sequencing data is useful for method development and comparison. Here, the authors developed SymSim, a simulator that explicitly models the main factors of variation in single cell data. |
format |
article |
author |
Xiuwei Zhang Chenling Xu Nir Yosef |
author_facet |
Xiuwei Zhang Chenling Xu Nir Yosef |
author_sort |
Xiuwei Zhang |
title |
Simulating multiple faceted variability in single cell RNA sequencing |
title_short |
Simulating multiple faceted variability in single cell RNA sequencing |
title_full |
Simulating multiple faceted variability in single cell RNA sequencing |
title_fullStr |
Simulating multiple faceted variability in single cell RNA sequencing |
title_full_unstemmed |
Simulating multiple faceted variability in single cell RNA sequencing |
title_sort |
simulating multiple faceted variability in single cell rna sequencing |
publisher |
Nature Portfolio |
publishDate |
2019 |
url |
https://doaj.org/article/0c024b34635d400b80a0b8fd1ba5c64c |
work_keys_str_mv |
AT xiuweizhang simulatingmultiplefacetedvariabilityinsinglecellrnasequencing AT chenlingxu simulatingmultiplefacetedvariabilityinsinglecellrnasequencing AT niryosef simulatingmultiplefacetedvariabilityinsinglecellrnasequencing |
_version_ |
1718380351240273920 |