Kindlin-2 mediates mechanotransduction in bone by regulating expression of Sclerostin in osteocytes

Kindlin-2 mediates mechanotransduction in bone by regulating expression of Sclerostin in osteocytes

Qin et al. show the involvement of Kindlin-2 in osteocyte mechanotransduction. They show Kindlin-2 mediates skeletal responses to mechanical stimulation through Smad 2/3 mediated inhibition of Sclerostin.

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Detalles Bibliográficos
Autores principales: Lei Qin, Xuekun Fu, Jing Ma, Manxia Lin, Peijun Zhang, Yishu Wang, Qinnan Yan, Chu Tao, Wen Liu, Bin Tang, Di Chen, Xiaochun Bai, Huiling Cao, Guozhi Xiao
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Biology (General)
QH301-705.5
Acceso en línea:https://doaj.org/article/0c081a3580bc408089962eec2ee0cb9b
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