A tumor-specific endogenous repetitive element is induced by herpesviruses

The human genome includes a large amount of repetitive sequence, such as human satellite II (HSATII), but their function remains largely unknown. Here, Nogalski et al. show that herpesvirus infection induces HSATII RNA expression, which in turn affects virus replication and cell motility.

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Autores principales:	Maciej T. Nogalski, Alexander Solovyov, Anupriya S. Kulkarni, Niyati Desai, Adam Oberstein, Arnold J. Levine, David T. Ting, Thomas Shenk, Benjamin D. Greenbaum
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/0c0a14c407d84879b5ec6d1592ca8488
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spelling	oai:doaj.org-article:0c0a14c407d84879b5ec6d1592ca84882021-12-02T14:39:00ZA tumor-specific endogenous repetitive element is induced by herpesviruses10.1038/s41467-018-07944-x2041-1723https://doaj.org/article/0c0a14c407d84879b5ec6d1592ca84882019-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-07944-xhttps://doaj.org/toc/2041-1723The human genome includes a large amount of repetitive sequence, such as human satellite II (HSATII), but their function remains largely unknown. Here, Nogalski et al. show that herpesvirus infection induces HSATII RNA expression, which in turn affects virus replication and cell motility.Maciej T. NogalskiAlexander SolovyovAnupriya S. KulkarniNiyati DesaiAdam ObersteinArnold J. LevineDavid T. TingThomas ShenkBenjamin D. GreenbaumNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Maciej T. Nogalski Alexander Solovyov Anupriya S. Kulkarni Niyati Desai Adam Oberstein Arnold J. Levine David T. Ting Thomas Shenk Benjamin D. Greenbaum A tumor-specific endogenous repetitive element is induced by herpesviruses
description	The human genome includes a large amount of repetitive sequence, such as human satellite II (HSATII), but their function remains largely unknown. Here, Nogalski et al. show that herpesvirus infection induces HSATII RNA expression, which in turn affects virus replication and cell motility.
format	article
author	Maciej T. Nogalski Alexander Solovyov Anupriya S. Kulkarni Niyati Desai Adam Oberstein Arnold J. Levine David T. Ting Thomas Shenk Benjamin D. Greenbaum
author_facet	Maciej T. Nogalski Alexander Solovyov Anupriya S. Kulkarni Niyati Desai Adam Oberstein Arnold J. Levine David T. Ting Thomas Shenk Benjamin D. Greenbaum
author_sort	Maciej T. Nogalski
title	A tumor-specific endogenous repetitive element is induced by herpesviruses
title_short	A tumor-specific endogenous repetitive element is induced by herpesviruses
title_full	A tumor-specific endogenous repetitive element is induced by herpesviruses
title_fullStr	A tumor-specific endogenous repetitive element is induced by herpesviruses
title_full_unstemmed	A tumor-specific endogenous repetitive element is induced by herpesviruses
title_sort	tumor-specific endogenous repetitive element is induced by herpesviruses
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/0c0a14c407d84879b5ec6d1592ca8488
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A tumor-specific endogenous repetitive element is induced by herpesviruses

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