One-pot three-component tandem annulation of 4-hydroxycoumarine with aldehyde and aromatic amines using graphene oxide as an efficient catalyst

Abstract A convenient and efficient solvent-free, facile, one-pot three-component graphene oxide catalysed approach has been described for the synthesis of chromeno-[4,3-b]quinolin-6-one derivatives from 4-hydroxycoumarin with aldehydes and aromatic amines. Graphene oxide (GO) has proved to be a new...

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Autores principales: Rabindranath Singha, Aminul Islam, Pranab Ghosh
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Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/0c0b1b4c9c5a49b681a5bd67978a109f
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spelling oai:doaj.org-article:0c0b1b4c9c5a49b681a5bd67978a109f2021-12-02T17:13:17ZOne-pot three-component tandem annulation of 4-hydroxycoumarine with aldehyde and aromatic amines using graphene oxide as an efficient catalyst10.1038/s41598-021-99360-32045-2322https://doaj.org/article/0c0b1b4c9c5a49b681a5bd67978a109f2021-10-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-99360-3https://doaj.org/toc/2045-2322Abstract A convenient and efficient solvent-free, facile, one-pot three-component graphene oxide catalysed approach has been described for the synthesis of chromeno-[4,3-b]quinolin-6-one derivatives from 4-hydroxycoumarin with aldehydes and aromatic amines. Graphene oxide (GO) has proved to be a new class of heterogeneous carbocatalyst which could be easily recovered and reused up to 5th run without significant loss of its catalytic activity. A broad scope of substrate applicability is offered and a plausible mechanism is also suggested for this developed protocol.Rabindranath SinghaAminul IslamPranab GhoshNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
institution DOAJ
collection DOAJ
language EN
topic Medicine
R
Science
Q
spellingShingle Medicine
R
Science
Q
Rabindranath Singha
Aminul Islam
Pranab Ghosh
One-pot three-component tandem annulation of 4-hydroxycoumarine with aldehyde and aromatic amines using graphene oxide as an efficient catalyst
description Abstract A convenient and efficient solvent-free, facile, one-pot three-component graphene oxide catalysed approach has been described for the synthesis of chromeno-[4,3-b]quinolin-6-one derivatives from 4-hydroxycoumarin with aldehydes and aromatic amines. Graphene oxide (GO) has proved to be a new class of heterogeneous carbocatalyst which could be easily recovered and reused up to 5th run without significant loss of its catalytic activity. A broad scope of substrate applicability is offered and a plausible mechanism is also suggested for this developed protocol.
format article
author Rabindranath Singha
Aminul Islam
Pranab Ghosh
author_facet Rabindranath Singha
Aminul Islam
Pranab Ghosh
author_sort Rabindranath Singha
title One-pot three-component tandem annulation of 4-hydroxycoumarine with aldehyde and aromatic amines using graphene oxide as an efficient catalyst
title_short One-pot three-component tandem annulation of 4-hydroxycoumarine with aldehyde and aromatic amines using graphene oxide as an efficient catalyst
title_full One-pot three-component tandem annulation of 4-hydroxycoumarine with aldehyde and aromatic amines using graphene oxide as an efficient catalyst
title_fullStr One-pot three-component tandem annulation of 4-hydroxycoumarine with aldehyde and aromatic amines using graphene oxide as an efficient catalyst
title_full_unstemmed One-pot three-component tandem annulation of 4-hydroxycoumarine with aldehyde and aromatic amines using graphene oxide as an efficient catalyst
title_sort one-pot three-component tandem annulation of 4-hydroxycoumarine with aldehyde and aromatic amines using graphene oxide as an efficient catalyst
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/0c0b1b4c9c5a49b681a5bd67978a109f
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AT aminulislam onepotthreecomponenttandemannulationof4hydroxycoumarinewithaldehydeandaromaticaminesusinggrapheneoxideasanefficientcatalyst
AT pranabghosh onepotthreecomponenttandemannulationof4hydroxycoumarinewithaldehydeandaromaticaminesusinggrapheneoxideasanefficientcatalyst
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