One-pot three-component tandem annulation of 4-hydroxycoumarine with aldehyde and aromatic amines using graphene oxide as an efficient catalyst
Abstract A convenient and efficient solvent-free, facile, one-pot three-component graphene oxide catalysed approach has been described for the synthesis of chromeno-[4,3-b]quinolin-6-one derivatives from 4-hydroxycoumarin with aldehydes and aromatic amines. Graphene oxide (GO) has proved to be a new...
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Nature Portfolio
2021
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oai:doaj.org-article:0c0b1b4c9c5a49b681a5bd67978a109f2021-12-02T17:13:17ZOne-pot three-component tandem annulation of 4-hydroxycoumarine with aldehyde and aromatic amines using graphene oxide as an efficient catalyst10.1038/s41598-021-99360-32045-2322https://doaj.org/article/0c0b1b4c9c5a49b681a5bd67978a109f2021-10-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-99360-3https://doaj.org/toc/2045-2322Abstract A convenient and efficient solvent-free, facile, one-pot three-component graphene oxide catalysed approach has been described for the synthesis of chromeno-[4,3-b]quinolin-6-one derivatives from 4-hydroxycoumarin with aldehydes and aromatic amines. Graphene oxide (GO) has proved to be a new class of heterogeneous carbocatalyst which could be easily recovered and reused up to 5th run without significant loss of its catalytic activity. A broad scope of substrate applicability is offered and a plausible mechanism is also suggested for this developed protocol.Rabindranath SinghaAminul IslamPranab GhoshNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-9 (2021) |
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Medicine R Science Q Rabindranath Singha Aminul Islam Pranab Ghosh One-pot three-component tandem annulation of 4-hydroxycoumarine with aldehyde and aromatic amines using graphene oxide as an efficient catalyst |
description |
Abstract A convenient and efficient solvent-free, facile, one-pot three-component graphene oxide catalysed approach has been described for the synthesis of chromeno-[4,3-b]quinolin-6-one derivatives from 4-hydroxycoumarin with aldehydes and aromatic amines. Graphene oxide (GO) has proved to be a new class of heterogeneous carbocatalyst which could be easily recovered and reused up to 5th run without significant loss of its catalytic activity. A broad scope of substrate applicability is offered and a plausible mechanism is also suggested for this developed protocol. |
format |
article |
author |
Rabindranath Singha Aminul Islam Pranab Ghosh |
author_facet |
Rabindranath Singha Aminul Islam Pranab Ghosh |
author_sort |
Rabindranath Singha |
title |
One-pot three-component tandem annulation of 4-hydroxycoumarine with aldehyde and aromatic amines using graphene oxide as an efficient catalyst |
title_short |
One-pot three-component tandem annulation of 4-hydroxycoumarine with aldehyde and aromatic amines using graphene oxide as an efficient catalyst |
title_full |
One-pot three-component tandem annulation of 4-hydroxycoumarine with aldehyde and aromatic amines using graphene oxide as an efficient catalyst |
title_fullStr |
One-pot three-component tandem annulation of 4-hydroxycoumarine with aldehyde and aromatic amines using graphene oxide as an efficient catalyst |
title_full_unstemmed |
One-pot three-component tandem annulation of 4-hydroxycoumarine with aldehyde and aromatic amines using graphene oxide as an efficient catalyst |
title_sort |
one-pot three-component tandem annulation of 4-hydroxycoumarine with aldehyde and aromatic amines using graphene oxide as an efficient catalyst |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/0c0b1b4c9c5a49b681a5bd67978a109f |
work_keys_str_mv |
AT rabindranathsingha onepotthreecomponenttandemannulationof4hydroxycoumarinewithaldehydeandaromaticaminesusinggrapheneoxideasanefficientcatalyst AT aminulislam onepotthreecomponenttandemannulationof4hydroxycoumarinewithaldehydeandaromaticaminesusinggrapheneoxideasanefficientcatalyst AT pranabghosh onepotthreecomponenttandemannulationof4hydroxycoumarinewithaldehydeandaromaticaminesusinggrapheneoxideasanefficientcatalyst |
_version_ |
1718381361808539648 |