Scalable recombinase-based gene expression cascades
There are few robust circuit architectures for sequential gene perturbations. Here, the authors use a modular recombinase-based design that sequentially edits loci, synchronizes cells, and deletes itself.
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Autores principales: | Tackhoon Kim, Benjamin Weinberg, Wilson Wong, Timothy K. Lu |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/0c21854435d549eeaf4ce8f46f2e69c0 |
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