Post-endocytic sorting of Plexin-D1 controls signal transduction and development of axonal and vascular circuits

Molecular mechanisms controlling axonal growth cone behaviour are only partially understood. Here the authors reveal a role of an adaptor protein GIPC1 in Plexin-D1 receptor recycling, and show that this process is required for axon track formation and vascular patterning in mice.

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Autores principales:	Katja Burk, Erik Mire, Anaïs Bellon, Mélanie Hocine, Jeremy Guillot, Filipa Moraes, Yutaka Yoshida, Michael Simons, Sophie Chauvet, Fanny Mann
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/0c33279192a44b8494aa04a9da0571f5
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spelling	oai:doaj.org-article:0c33279192a44b8494aa04a9da0571f52021-12-02T17:06:05ZPost-endocytic sorting of Plexin-D1 controls signal transduction and development of axonal and vascular circuits10.1038/ncomms145082041-1723https://doaj.org/article/0c33279192a44b8494aa04a9da0571f52017-02-01T00:00:00Zhttps://doi.org/10.1038/ncomms14508https://doaj.org/toc/2041-1723Molecular mechanisms controlling axonal growth cone behaviour are only partially understood. Here the authors reveal a role of an adaptor protein GIPC1 in Plexin-D1 receptor recycling, and show that this process is required for axon track formation and vascular patterning in mice.Katja BurkErik MireAnaïs BellonMélanie HocineJeremy GuillotFilipa MoraesYutaka YoshidaMichael SimonsSophie ChauvetFanny MannNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-17 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Katja Burk Erik Mire Anaïs Bellon Mélanie Hocine Jeremy Guillot Filipa Moraes Yutaka Yoshida Michael Simons Sophie Chauvet Fanny Mann Post-endocytic sorting of Plexin-D1 controls signal transduction and development of axonal and vascular circuits
description	Molecular mechanisms controlling axonal growth cone behaviour are only partially understood. Here the authors reveal a role of an adaptor protein GIPC1 in Plexin-D1 receptor recycling, and show that this process is required for axon track formation and vascular patterning in mice.
format	article
author	Katja Burk Erik Mire Anaïs Bellon Mélanie Hocine Jeremy Guillot Filipa Moraes Yutaka Yoshida Michael Simons Sophie Chauvet Fanny Mann
author_facet	Katja Burk Erik Mire Anaïs Bellon Mélanie Hocine Jeremy Guillot Filipa Moraes Yutaka Yoshida Michael Simons Sophie Chauvet Fanny Mann
author_sort	Katja Burk
title	Post-endocytic sorting of Plexin-D1 controls signal transduction and development of axonal and vascular circuits
title_short	Post-endocytic sorting of Plexin-D1 controls signal transduction and development of axonal and vascular circuits
title_full	Post-endocytic sorting of Plexin-D1 controls signal transduction and development of axonal and vascular circuits
title_fullStr	Post-endocytic sorting of Plexin-D1 controls signal transduction and development of axonal and vascular circuits
title_full_unstemmed	Post-endocytic sorting of Plexin-D1 controls signal transduction and development of axonal and vascular circuits
title_sort	post-endocytic sorting of plexin-d1 controls signal transduction and development of axonal and vascular circuits
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/0c33279192a44b8494aa04a9da0571f5
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Post-endocytic sorting of Plexin-D1 controls signal transduction and development of axonal and vascular circuits

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