Modeling the process of human tumorigenesis

A better understanding of the earliest stages of human cancer formation can enable future improvements in early detection, diagnosis and treatment. In this review, the authors summarize the methods enablingde novotumorigenesis protocols to be applied to human cells and the insights derived from them...

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Autores principales: Sneha Balani, Long V. Nguyen, Connie J. Eaves
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/0c37a9958528442f9a879a02edc257c5
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Sumario:A better understanding of the earliest stages of human cancer formation can enable future improvements in early detection, diagnosis and treatment. In this review, the authors summarize the methods enablingde novotumorigenesis protocols to be applied to human cells and the insights derived from them to date, as well as the exciting and relevant technical developments anticipated to extend even further the utility of these strategies.