The molecular chaperones DNAJB6 and Hsp70 cooperate to suppress α-synuclein aggregation
Abstract A major hallmark of Parkinson’s disease (PD) is the presence of Lewy bodies (LBs) in certain neuronal tissues. LBs are protein-rich inclusions, in which α-synuclein (α-syn) is the most abundant protein. Since these inclusions are not present in healthy individuals, despite the high concentr...
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Autores principales: | Francesco A. Aprile, Emma Källstig, Galina Limorenko, Michele Vendruscolo, David Ron, Christian Hansen |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
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Materias: | |
Acceso en línea: | https://doaj.org/article/0c38ccc85024480b8c6ce7d146030f9f |
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