Embracing Metagenomic Complexity with a Genome-Free Approach
A central paradigm in microbiome data analysis, which we term the genome-centric paradigm, is that a linear (nonbranching) DNA sequence is the ideal representation of a microbial genome. This representation is natural, as microbes indeed have nonbranching genomes.
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American Society for Microbiology
2021
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oai:doaj.org-article:0c391919eda5471995e32a96db65695e2021-12-02T18:18:34ZEmbracing Metagenomic Complexity with a Genome-Free Approach2379-507710.1128/mSystems.00816-21https://doaj.org/article/0c391919eda5471995e32a96db65695e2021-08-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/mSystems.00816-21https://doaj.org/toc/2379-5077 A central paradigm in microbiome data analysis, which we term the genome-centric paradigm, is that a linear (nonbranching) DNA sequence is the ideal representation of a microbial genome. This representation is natural, as microbes indeed have nonbranching genomes.Izaak ColemanTal KoremAmerican Society for MicrobiologyarticleMicrobiologyQR1-502ENmSystems, Vol 6, Iss 4 (2021) |
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DOAJ |
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topic |
Microbiology QR1-502 |
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Microbiology QR1-502 Izaak Coleman Tal Korem Embracing Metagenomic Complexity with a Genome-Free Approach |
description |
A central paradigm in microbiome data analysis, which we term the genome-centric paradigm, is that a linear (nonbranching) DNA sequence is the ideal representation of a microbial genome. This representation is natural, as microbes indeed have nonbranching genomes. |
format |
article |
author |
Izaak Coleman Tal Korem |
author_facet |
Izaak Coleman Tal Korem |
author_sort |
Izaak Coleman |
title |
Embracing Metagenomic Complexity with a Genome-Free Approach |
title_short |
Embracing Metagenomic Complexity with a Genome-Free Approach |
title_full |
Embracing Metagenomic Complexity with a Genome-Free Approach |
title_fullStr |
Embracing Metagenomic Complexity with a Genome-Free Approach |
title_full_unstemmed |
Embracing Metagenomic Complexity with a Genome-Free Approach |
title_sort |
embracing metagenomic complexity with a genome-free approach |
publisher |
American Society for Microbiology |
publishDate |
2021 |
url |
https://doaj.org/article/0c391919eda5471995e32a96db65695e |
work_keys_str_mv |
AT izaakcoleman embracingmetagenomiccomplexitywithagenomefreeapproach AT talkorem embracingmetagenomiccomplexitywithagenomefreeapproach |
_version_ |
1718378197113896960 |