Embracing Metagenomic Complexity with a Genome-Free Approach

A central paradigm in microbiome data analysis, which we term the genome-centric paradigm, is that a linear (nonbranching) DNA sequence is the ideal representation of a microbial genome. This representation is natural, as microbes indeed have nonbranching genomes.

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Autores principales: Izaak Coleman, Tal Korem
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2021
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Acceso en línea:https://doaj.org/article/0c391919eda5471995e32a96db65695e
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spelling oai:doaj.org-article:0c391919eda5471995e32a96db65695e2021-12-02T18:18:34ZEmbracing Metagenomic Complexity with a Genome-Free Approach2379-507710.1128/mSystems.00816-21https://doaj.org/article/0c391919eda5471995e32a96db65695e2021-08-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/mSystems.00816-21https://doaj.org/toc/2379-5077 A central paradigm in microbiome data analysis, which we term the genome-centric paradigm, is that a linear (nonbranching) DNA sequence is the ideal representation of a microbial genome. This representation is natural, as microbes indeed have nonbranching genomes.Izaak ColemanTal KoremAmerican Society for MicrobiologyarticleMicrobiologyQR1-502ENmSystems, Vol 6, Iss 4 (2021)
institution DOAJ
collection DOAJ
language EN
topic Microbiology
QR1-502
spellingShingle Microbiology
QR1-502
Izaak Coleman
Tal Korem
Embracing Metagenomic Complexity with a Genome-Free Approach
description A central paradigm in microbiome data analysis, which we term the genome-centric paradigm, is that a linear (nonbranching) DNA sequence is the ideal representation of a microbial genome. This representation is natural, as microbes indeed have nonbranching genomes.
format article
author Izaak Coleman
Tal Korem
author_facet Izaak Coleman
Tal Korem
author_sort Izaak Coleman
title Embracing Metagenomic Complexity with a Genome-Free Approach
title_short Embracing Metagenomic Complexity with a Genome-Free Approach
title_full Embracing Metagenomic Complexity with a Genome-Free Approach
title_fullStr Embracing Metagenomic Complexity with a Genome-Free Approach
title_full_unstemmed Embracing Metagenomic Complexity with a Genome-Free Approach
title_sort embracing metagenomic complexity with a genome-free approach
publisher American Society for Microbiology
publishDate 2021
url https://doaj.org/article/0c391919eda5471995e32a96db65695e
work_keys_str_mv AT izaakcoleman embracingmetagenomiccomplexitywithagenomefreeapproach
AT talkorem embracingmetagenomiccomplexitywithagenomefreeapproach
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