The pore structure of Clostridium perfringens epsilon toxin

Epsilon toxin (Etx) is a potent pore forming toxin (PFT) produced by Clostridium perfringens. Here authors show the cryo-EM structure of the Etx pore assembled on the membrane of susceptible cells and shed light on pore formation and mutant phenotypes.

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Autores principales:	Christos G. Savva, Alice R. Clark, Claire E. Naylor, Michel R. Popoff, David S. Moss, Ajit K. Basak, Richard W. Titball, Monika Bokori-Brown
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/0c3cc9c7ec024b4ca980cfc36be9bbed
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spelling	oai:doaj.org-article:0c3cc9c7ec024b4ca980cfc36be9bbed2021-12-02T17:02:17ZThe pore structure of Clostridium perfringens epsilon toxin10.1038/s41467-019-10645-82041-1723https://doaj.org/article/0c3cc9c7ec024b4ca980cfc36be9bbed2019-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-10645-8https://doaj.org/toc/2041-1723Epsilon toxin (Etx) is a potent pore forming toxin (PFT) produced by Clostridium perfringens. Here authors show the cryo-EM structure of the Etx pore assembled on the membrane of susceptible cells and shed light on pore formation and mutant phenotypes.Christos G. SavvaAlice R. ClarkClaire E. NaylorMichel R. PopoffDavid S. MossAjit K. BasakRichard W. TitballMonika Bokori-BrownNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Christos G. Savva Alice R. Clark Claire E. Naylor Michel R. Popoff David S. Moss Ajit K. Basak Richard W. Titball Monika Bokori-Brown The pore structure of Clostridium perfringens epsilon toxin
description	Epsilon toxin (Etx) is a potent pore forming toxin (PFT) produced by Clostridium perfringens. Here authors show the cryo-EM structure of the Etx pore assembled on the membrane of susceptible cells and shed light on pore formation and mutant phenotypes.
format	article
author	Christos G. Savva Alice R. Clark Claire E. Naylor Michel R. Popoff David S. Moss Ajit K. Basak Richard W. Titball Monika Bokori-Brown
author_facet	Christos G. Savva Alice R. Clark Claire E. Naylor Michel R. Popoff David S. Moss Ajit K. Basak Richard W. Titball Monika Bokori-Brown
author_sort	Christos G. Savva
title	The pore structure of Clostridium perfringens epsilon toxin
title_short	The pore structure of Clostridium perfringens epsilon toxin
title_full	The pore structure of Clostridium perfringens epsilon toxin
title_fullStr	The pore structure of Clostridium perfringens epsilon toxin
title_full_unstemmed	The pore structure of Clostridium perfringens epsilon toxin
title_sort	pore structure of clostridium perfringens epsilon toxin
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/0c3cc9c7ec024b4ca980cfc36be9bbed
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The pore structure of Clostridium perfringens epsilon toxin

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