Identification of a common mesenchymal stromal progenitor for the adult haematopoietic niche

How the environment of the niche regulates haematopoietic stem cells (HSC) is unclear. Here, the authors identify a mesenchymal stromal progenitor hierarchy and identify Sca1+ cells as common progenitors for mesenchymal stromal cells in the adult niche that provide a supportive environment for hemat...

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Autores principales: Xingbin Hu, Mayra Garcia, Lihong Weng, Xiaoman Jung, Jodi L. Murakami, Bijender Kumar, Charles D. Warden, Ivan Todorov, Ching-Cheng Chen
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Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/0c3e26f6e868438cbe5484c31c1ee35f
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spelling oai:doaj.org-article:0c3e26f6e868438cbe5484c31c1ee35f2021-12-02T16:57:28ZIdentification of a common mesenchymal stromal progenitor for the adult haematopoietic niche10.1038/ncomms130952041-1723https://doaj.org/article/0c3e26f6e868438cbe5484c31c1ee35f2016-10-01T00:00:00Zhttps://doi.org/10.1038/ncomms13095https://doaj.org/toc/2041-1723How the environment of the niche regulates haematopoietic stem cells (HSC) is unclear. Here, the authors identify a mesenchymal stromal progenitor hierarchy and identify Sca1+ cells as common progenitors for mesenchymal stromal cells in the adult niche that provide a supportive environment for hematopoiesis.Xingbin HuMayra GarciaLihong WengXiaoman JungJodi L. MurakamiBijender KumarCharles D. WardenIvan TodorovChing-Cheng ChenNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Xingbin Hu
Mayra Garcia
Lihong Weng
Xiaoman Jung
Jodi L. Murakami
Bijender Kumar
Charles D. Warden
Ivan Todorov
Ching-Cheng Chen
Identification of a common mesenchymal stromal progenitor for the adult haematopoietic niche
description How the environment of the niche regulates haematopoietic stem cells (HSC) is unclear. Here, the authors identify a mesenchymal stromal progenitor hierarchy and identify Sca1+ cells as common progenitors for mesenchymal stromal cells in the adult niche that provide a supportive environment for hematopoiesis.
format article
author Xingbin Hu
Mayra Garcia
Lihong Weng
Xiaoman Jung
Jodi L. Murakami
Bijender Kumar
Charles D. Warden
Ivan Todorov
Ching-Cheng Chen
author_facet Xingbin Hu
Mayra Garcia
Lihong Weng
Xiaoman Jung
Jodi L. Murakami
Bijender Kumar
Charles D. Warden
Ivan Todorov
Ching-Cheng Chen
author_sort Xingbin Hu
title Identification of a common mesenchymal stromal progenitor for the adult haematopoietic niche
title_short Identification of a common mesenchymal stromal progenitor for the adult haematopoietic niche
title_full Identification of a common mesenchymal stromal progenitor for the adult haematopoietic niche
title_fullStr Identification of a common mesenchymal stromal progenitor for the adult haematopoietic niche
title_full_unstemmed Identification of a common mesenchymal stromal progenitor for the adult haematopoietic niche
title_sort identification of a common mesenchymal stromal progenitor for the adult haematopoietic niche
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/0c3e26f6e868438cbe5484c31c1ee35f
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