Differentiating features of OCT angiography in diabetic macular edema

Abstract The purpose of current study was to evaluate different optical coherence tomography angiography (OCTA) metrics in eyes with diabetic retinopathy with and without diabetic macular edema (DME). In this retrospective study, macular OCTA images of eyes with non-proliferative or proliferative di...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Reza Mirshahi, Hamid Riazi-Esfahani, Elias Khalili Pour, Kaveh Fadakar, Parsa Yarmohamadi, Sayyed Amirpooya Alemzadeh, Samira Chaibakhsh, Khalil Ghasemi Falavarjani
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
R
Q
Acceso en línea:https://doaj.org/article/0c468629345b42b38caa66cc38005490
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:0c468629345b42b38caa66cc38005490
record_format dspace
spelling oai:doaj.org-article:0c468629345b42b38caa66cc380054902021-12-05T12:12:35ZDifferentiating features of OCT angiography in diabetic macular edema10.1038/s41598-021-02859-y2045-2322https://doaj.org/article/0c468629345b42b38caa66cc380054902021-12-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-02859-yhttps://doaj.org/toc/2045-2322Abstract The purpose of current study was to evaluate different optical coherence tomography angiography (OCTA) metrics in eyes with diabetic retinopathy with and without diabetic macular edema (DME). In this retrospective study, macular OCTA images of eyes with non-proliferative or proliferative diabetic retinopathy were evaluated. Vascular density, vascular complexity and non-perfusion densities were compared between eyes with and without DME. One-hundred-thirty-eight eyes of 92 diabetic patients including 49 eyes with DME were included. In multivariate analysis, the presence of DME was positively associated with geometric perfusion deficit (GPD) in superficial capillary plexus (SCP), capillary non-perfusion (CNP) of SCP, and GPD in deep capillary plexus (DCP) (all P < 0.05). In eyes with DME, central foveal thickness was associated with VD ratio (SCP/DCP) (P = 0.001) and FAZ area (P = 0.001). In conclusion, in eyes with diabetic retinopathy, the presence of DME was associated with more extensive capillary non-perfusion compared to those with no macular edema.Reza MirshahiHamid Riazi-EsfahaniElias Khalili PourKaveh FadakarParsa YarmohamadiSayyed Amirpooya AlemzadehSamira ChaibakhshKhalil Ghasemi FalavarjaniNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-7 (2021)
institution DOAJ
collection DOAJ
language EN
topic Medicine
R
Science
Q
spellingShingle Medicine
R
Science
Q
Reza Mirshahi
Hamid Riazi-Esfahani
Elias Khalili Pour
Kaveh Fadakar
Parsa Yarmohamadi
Sayyed Amirpooya Alemzadeh
Samira Chaibakhsh
Khalil Ghasemi Falavarjani
Differentiating features of OCT angiography in diabetic macular edema
description Abstract The purpose of current study was to evaluate different optical coherence tomography angiography (OCTA) metrics in eyes with diabetic retinopathy with and without diabetic macular edema (DME). In this retrospective study, macular OCTA images of eyes with non-proliferative or proliferative diabetic retinopathy were evaluated. Vascular density, vascular complexity and non-perfusion densities were compared between eyes with and without DME. One-hundred-thirty-eight eyes of 92 diabetic patients including 49 eyes with DME were included. In multivariate analysis, the presence of DME was positively associated with geometric perfusion deficit (GPD) in superficial capillary plexus (SCP), capillary non-perfusion (CNP) of SCP, and GPD in deep capillary plexus (DCP) (all P < 0.05). In eyes with DME, central foveal thickness was associated with VD ratio (SCP/DCP) (P = 0.001) and FAZ area (P = 0.001). In conclusion, in eyes with diabetic retinopathy, the presence of DME was associated with more extensive capillary non-perfusion compared to those with no macular edema.
format article
author Reza Mirshahi
Hamid Riazi-Esfahani
Elias Khalili Pour
Kaveh Fadakar
Parsa Yarmohamadi
Sayyed Amirpooya Alemzadeh
Samira Chaibakhsh
Khalil Ghasemi Falavarjani
author_facet Reza Mirshahi
Hamid Riazi-Esfahani
Elias Khalili Pour
Kaveh Fadakar
Parsa Yarmohamadi
Sayyed Amirpooya Alemzadeh
Samira Chaibakhsh
Khalil Ghasemi Falavarjani
author_sort Reza Mirshahi
title Differentiating features of OCT angiography in diabetic macular edema
title_short Differentiating features of OCT angiography in diabetic macular edema
title_full Differentiating features of OCT angiography in diabetic macular edema
title_fullStr Differentiating features of OCT angiography in diabetic macular edema
title_full_unstemmed Differentiating features of OCT angiography in diabetic macular edema
title_sort differentiating features of oct angiography in diabetic macular edema
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/0c468629345b42b38caa66cc38005490
work_keys_str_mv AT rezamirshahi differentiatingfeaturesofoctangiographyindiabeticmacularedema
AT hamidriaziesfahani differentiatingfeaturesofoctangiographyindiabeticmacularedema
AT eliaskhalilipour differentiatingfeaturesofoctangiographyindiabeticmacularedema
AT kavehfadakar differentiatingfeaturesofoctangiographyindiabeticmacularedema
AT parsayarmohamadi differentiatingfeaturesofoctangiographyindiabeticmacularedema
AT sayyedamirpooyaalemzadeh differentiatingfeaturesofoctangiographyindiabeticmacularedema
AT samirachaibakhsh differentiatingfeaturesofoctangiographyindiabeticmacularedema
AT khalilghasemifalavarjani differentiatingfeaturesofoctangiographyindiabeticmacularedema
_version_ 1718372116427964416