Differentiating features of OCT angiography in diabetic macular edema
Abstract The purpose of current study was to evaluate different optical coherence tomography angiography (OCTA) metrics in eyes with diabetic retinopathy with and without diabetic macular edema (DME). In this retrospective study, macular OCTA images of eyes with non-proliferative or proliferative di...
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Nature Portfolio
2021
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oai:doaj.org-article:0c468629345b42b38caa66cc380054902021-12-05T12:12:35ZDifferentiating features of OCT angiography in diabetic macular edema10.1038/s41598-021-02859-y2045-2322https://doaj.org/article/0c468629345b42b38caa66cc380054902021-12-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-02859-yhttps://doaj.org/toc/2045-2322Abstract The purpose of current study was to evaluate different optical coherence tomography angiography (OCTA) metrics in eyes with diabetic retinopathy with and without diabetic macular edema (DME). In this retrospective study, macular OCTA images of eyes with non-proliferative or proliferative diabetic retinopathy were evaluated. Vascular density, vascular complexity and non-perfusion densities were compared between eyes with and without DME. One-hundred-thirty-eight eyes of 92 diabetic patients including 49 eyes with DME were included. In multivariate analysis, the presence of DME was positively associated with geometric perfusion deficit (GPD) in superficial capillary plexus (SCP), capillary non-perfusion (CNP) of SCP, and GPD in deep capillary plexus (DCP) (all P < 0.05). In eyes with DME, central foveal thickness was associated with VD ratio (SCP/DCP) (P = 0.001) and FAZ area (P = 0.001). In conclusion, in eyes with diabetic retinopathy, the presence of DME was associated with more extensive capillary non-perfusion compared to those with no macular edema.Reza MirshahiHamid Riazi-EsfahaniElias Khalili PourKaveh FadakarParsa YarmohamadiSayyed Amirpooya AlemzadehSamira ChaibakhshKhalil Ghasemi FalavarjaniNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-7 (2021) |
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Medicine R Science Q Reza Mirshahi Hamid Riazi-Esfahani Elias Khalili Pour Kaveh Fadakar Parsa Yarmohamadi Sayyed Amirpooya Alemzadeh Samira Chaibakhsh Khalil Ghasemi Falavarjani Differentiating features of OCT angiography in diabetic macular edema |
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Abstract The purpose of current study was to evaluate different optical coherence tomography angiography (OCTA) metrics in eyes with diabetic retinopathy with and without diabetic macular edema (DME). In this retrospective study, macular OCTA images of eyes with non-proliferative or proliferative diabetic retinopathy were evaluated. Vascular density, vascular complexity and non-perfusion densities were compared between eyes with and without DME. One-hundred-thirty-eight eyes of 92 diabetic patients including 49 eyes with DME were included. In multivariate analysis, the presence of DME was positively associated with geometric perfusion deficit (GPD) in superficial capillary plexus (SCP), capillary non-perfusion (CNP) of SCP, and GPD in deep capillary plexus (DCP) (all P < 0.05). In eyes with DME, central foveal thickness was associated with VD ratio (SCP/DCP) (P = 0.001) and FAZ area (P = 0.001). In conclusion, in eyes with diabetic retinopathy, the presence of DME was associated with more extensive capillary non-perfusion compared to those with no macular edema. |
format |
article |
author |
Reza Mirshahi Hamid Riazi-Esfahani Elias Khalili Pour Kaveh Fadakar Parsa Yarmohamadi Sayyed Amirpooya Alemzadeh Samira Chaibakhsh Khalil Ghasemi Falavarjani |
author_facet |
Reza Mirshahi Hamid Riazi-Esfahani Elias Khalili Pour Kaveh Fadakar Parsa Yarmohamadi Sayyed Amirpooya Alemzadeh Samira Chaibakhsh Khalil Ghasemi Falavarjani |
author_sort |
Reza Mirshahi |
title |
Differentiating features of OCT angiography in diabetic macular edema |
title_short |
Differentiating features of OCT angiography in diabetic macular edema |
title_full |
Differentiating features of OCT angiography in diabetic macular edema |
title_fullStr |
Differentiating features of OCT angiography in diabetic macular edema |
title_full_unstemmed |
Differentiating features of OCT angiography in diabetic macular edema |
title_sort |
differentiating features of oct angiography in diabetic macular edema |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/0c468629345b42b38caa66cc38005490 |
work_keys_str_mv |
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