Transcranial static magnetic stimulation over the motor cortex can facilitate the contralateral cortical excitability in human

Abstract Transcranial static magnetic stimulation (tSMS) has been focused as a new non-invasive brain stimulation, which can suppress the human cortical excitability just below the magnet. However, the non-regional effects of tSMS via brain network have been rarely studied so far. We investigated wh...

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Autores principales:	Yasuyuki Takamatsu, Satoko Koganemaru, Tatsunori Watanabe, Sumiya Shibata, Yoshihiro Yukawa, Masatoshi Minakuchi, Ryota Shimomura, Tatsuya Mima
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/0c50462978cf4c31aa77e570b94a411a
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spelling	oai:doaj.org-article:0c50462978cf4c31aa77e570b94a411a2021-12-02T13:33:51ZTranscranial static magnetic stimulation over the motor cortex can facilitate the contralateral cortical excitability in human10.1038/s41598-021-84823-42045-2322https://doaj.org/article/0c50462978cf4c31aa77e570b94a411a2021-03-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-84823-4https://doaj.org/toc/2045-2322Abstract Transcranial static magnetic stimulation (tSMS) has been focused as a new non-invasive brain stimulation, which can suppress the human cortical excitability just below the magnet. However, the non-regional effects of tSMS via brain network have been rarely studied so far. We investigated whether tSMS over the left primary motor cortex (M1) can facilitate the right M1 in healthy subjects, based on the hypothesis that the functional suppression of M1 can cause the paradoxical functional facilitation of the contralateral M1 via the reduction of interhemispheric inhibition (IHI) between the bilateral M1. This study was double-blind crossover trial. We measured the corticospinal excitability in both M1 and IHI from the left to right M1 by recording motor evoked potentials from first dorsal interosseous muscles using single-pulse and paired-pulse transcranial magnetic stimulation before and after the tSMS intervention for 30 min. We found that the corticospinal excitability of the left M1 decreased, while that of the right M1 increased after tSMS. Moreover, the evaluation of IHI revealed the reduced inhibition from the left to the right M1. Our findings provide new insights on the mechanistic understanding of neuromodulatory effects of tSMS in human.Yasuyuki TakamatsuSatoko KoganemaruTatsunori WatanabeSumiya ShibataYoshihiro YukawaMasatoshi MinakuchiRyota ShimomuraTatsuya MimaNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Yasuyuki Takamatsu Satoko Koganemaru Tatsunori Watanabe Sumiya Shibata Yoshihiro Yukawa Masatoshi Minakuchi Ryota Shimomura Tatsuya Mima Transcranial static magnetic stimulation over the motor cortex can facilitate the contralateral cortical excitability in human
description	Abstract Transcranial static magnetic stimulation (tSMS) has been focused as a new non-invasive brain stimulation, which can suppress the human cortical excitability just below the magnet. However, the non-regional effects of tSMS via brain network have been rarely studied so far. We investigated whether tSMS over the left primary motor cortex (M1) can facilitate the right M1 in healthy subjects, based on the hypothesis that the functional suppression of M1 can cause the paradoxical functional facilitation of the contralateral M1 via the reduction of interhemispheric inhibition (IHI) between the bilateral M1. This study was double-blind crossover trial. We measured the corticospinal excitability in both M1 and IHI from the left to right M1 by recording motor evoked potentials from first dorsal interosseous muscles using single-pulse and paired-pulse transcranial magnetic stimulation before and after the tSMS intervention for 30 min. We found that the corticospinal excitability of the left M1 decreased, while that of the right M1 increased after tSMS. Moreover, the evaluation of IHI revealed the reduced inhibition from the left to the right M1. Our findings provide new insights on the mechanistic understanding of neuromodulatory effects of tSMS in human.
format	article
author	Yasuyuki Takamatsu Satoko Koganemaru Tatsunori Watanabe Sumiya Shibata Yoshihiro Yukawa Masatoshi Minakuchi Ryota Shimomura Tatsuya Mima
author_facet	Yasuyuki Takamatsu Satoko Koganemaru Tatsunori Watanabe Sumiya Shibata Yoshihiro Yukawa Masatoshi Minakuchi Ryota Shimomura Tatsuya Mima
author_sort	Yasuyuki Takamatsu
title	Transcranial static magnetic stimulation over the motor cortex can facilitate the contralateral cortical excitability in human
title_short	Transcranial static magnetic stimulation over the motor cortex can facilitate the contralateral cortical excitability in human
title_full	Transcranial static magnetic stimulation over the motor cortex can facilitate the contralateral cortical excitability in human
title_fullStr	Transcranial static magnetic stimulation over the motor cortex can facilitate the contralateral cortical excitability in human
title_full_unstemmed	Transcranial static magnetic stimulation over the motor cortex can facilitate the contralateral cortical excitability in human
title_sort	transcranial static magnetic stimulation over the motor cortex can facilitate the contralateral cortical excitability in human
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/0c50462978cf4c31aa77e570b94a411a
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_version_	1718392778365337600

Transcranial static magnetic stimulation over the motor cortex can facilitate the contralateral cortical excitability in human

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