Pronounced proliferation of non-beta cells in response to beta-cell mitogens in isolated human islets of Langerhans

Abstract The potential to treat diabetes by increasing beta-cell mass is driving a major effort to identify beta-cell mitogens. Demonstration of mitogen activity in human beta cells is frequently performed in ex vivo assays. However, reported disparities in the efficacy of beta-cell mitogens led us...

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Autores principales: Hasna Maachi, Julien Ghislain, Caroline Tremblay, Vincent Poitout
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/0c5672ccf4384164a7461795c4eafad4
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