Pronounced proliferation of non-beta cells in response to beta-cell mitogens in isolated human islets of Langerhans
Abstract The potential to treat diabetes by increasing beta-cell mass is driving a major effort to identify beta-cell mitogens. Demonstration of mitogen activity in human beta cells is frequently performed in ex vivo assays. However, reported disparities in the efficacy of beta-cell mitogens led us...
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Autores principales: | Hasna Maachi, Julien Ghislain, Caroline Tremblay, Vincent Poitout |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/0c5672ccf4384164a7461795c4eafad4 |
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