hHGF overexpression in myoblast sheets enhances their angiogenic potential in rat chronic heart failure.

After severe myocardial infarction (MI), heart failure results from ischemia, fibrosis, and remodeling. A promising therapy to enhance cardiac function and induce therapeutic angiogenesis via a paracrine mechanism in MI is myoblast sheet transplantation. We hypothesized that in a rat model of MI-ind...

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Autores principales: Antti Siltanen, Katsukiyo Kitabayashi, Päivi Lakkisto, Johanna Mäkelä, Tommi Pätilä, Masamichi Ono, Ilkka Tikkanen, Yoshiki Sawa, Esko Kankuri, Ari Harjula
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2011
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Acceso en línea:https://doaj.org/article/0c66ad6628e44f3797327e5ef929bed1
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