Prostaglandin E2 glyceryl ester is an endogenous agonist of the nucleotide receptor P2Y6

Prostaglandin E2 glyceryl ester is an endogenous agonist of the nucleotide receptor P2Y6

Abstract Cyclooxygenase-2 catalyses the biosynthesis of prostaglandins from arachidonic acid but also the biosynthesis of prostaglandin glycerol esters (PG-Gs) from 2-arachidonoylglycerol. Previous studies identified PG-Gs as signalling molecules involved in inflammation. Thus, the glyceryl ester of...

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Autores principales: Antje Brüser, Anne Zimmermann, Brenda C. Crews, Gregory Sliwoski, Jens Meiler, Gabriele M. König, Evi Kostenis, Vera Lede, Lawrence J. Marnett, Torsten Schöneberg
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Medicine
R
Science
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Acceso en línea:https://doaj.org/article/0c6b5a4f249e46d79caac5439349ac48
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