Human neuroepithelial stem cell regional specificity enables spinal cord repair through a relay circuit

The optimal type or regional origin of stem cells for regenerative applications in the nervous system has not yet been established. Here the authors show that human neuroepithelial stem cells from the developing spinal cord, but not those from the developing cortex, show good host-graft interaction...

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Autores principales:	Maria Teresa Dell’Anno, Xingxing Wang, Marco Onorati, Mingfeng Li, Francesca Talpo, Yuichi Sekine, Shaojie Ma, Fuchen Liu, William B. J. Cafferty, Nenad Sestan, Stephen M. Strittmatter
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/0c6bf4dc8dc74542a0664aa648168a87
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spelling	oai:doaj.org-article:0c6bf4dc8dc74542a0664aa648168a872021-12-02T14:40:30ZHuman neuroepithelial stem cell regional specificity enables spinal cord repair through a relay circuit10.1038/s41467-018-05844-82041-1723https://doaj.org/article/0c6bf4dc8dc74542a0664aa648168a872018-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-05844-8https://doaj.org/toc/2041-1723The optimal type or regional origin of stem cells for regenerative applications in the nervous system has not yet been established. Here the authors show that human neuroepithelial stem cells from the developing spinal cord, but not those from the developing cortex, show good host-graft interaction when transplanted to rodent models of spinal cord injury.Maria Teresa Dell’AnnoXingxing WangMarco OnoratiMingfeng LiFrancesca TalpoYuichi SekineShaojie MaFuchen LiuWilliam B. J. CaffertyNenad SestanStephen M. StrittmatterNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Maria Teresa Dell’Anno Xingxing Wang Marco Onorati Mingfeng Li Francesca Talpo Yuichi Sekine Shaojie Ma Fuchen Liu William B. J. Cafferty Nenad Sestan Stephen M. Strittmatter Human neuroepithelial stem cell regional specificity enables spinal cord repair through a relay circuit
description	The optimal type or regional origin of stem cells for regenerative applications in the nervous system has not yet been established. Here the authors show that human neuroepithelial stem cells from the developing spinal cord, but not those from the developing cortex, show good host-graft interaction when transplanted to rodent models of spinal cord injury.
format	article
author	Maria Teresa Dell’Anno Xingxing Wang Marco Onorati Mingfeng Li Francesca Talpo Yuichi Sekine Shaojie Ma Fuchen Liu William B. J. Cafferty Nenad Sestan Stephen M. Strittmatter
author_facet	Maria Teresa Dell’Anno Xingxing Wang Marco Onorati Mingfeng Li Francesca Talpo Yuichi Sekine Shaojie Ma Fuchen Liu William B. J. Cafferty Nenad Sestan Stephen M. Strittmatter
author_sort	Maria Teresa Dell’Anno
title	Human neuroepithelial stem cell regional specificity enables spinal cord repair through a relay circuit
title_short	Human neuroepithelial stem cell regional specificity enables spinal cord repair through a relay circuit
title_full	Human neuroepithelial stem cell regional specificity enables spinal cord repair through a relay circuit
title_fullStr	Human neuroepithelial stem cell regional specificity enables spinal cord repair through a relay circuit
title_full_unstemmed	Human neuroepithelial stem cell regional specificity enables spinal cord repair through a relay circuit
title_sort	human neuroepithelial stem cell regional specificity enables spinal cord repair through a relay circuit
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/0c6bf4dc8dc74542a0664aa648168a87
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Human neuroepithelial stem cell regional specificity enables spinal cord repair through a relay circuit

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