Major Neutrophil-Derived Soluble Mediators Associate With Baseline Lung Pathology and Post-Treatment Recovery in Tuberculosis Patients

Major Neutrophil-Derived Soluble Mediators Associate With Baseline Lung Pathology and Post-Treatment Recovery in Tuberculosis Patients

BackgroundThe inflammatory response to Mycobacterium tuberculosis results in variable degrees of lung pathology during active TB (ATB) with central involvement of neutrophils. Little is known about neutrophil-derived mediators and their role in disease severity at baseline and recovery upon TB treat...

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Autores principales: Caleb Nwongbouwoh Muefong, Olumuyiwa Owolabi, Simon Donkor, Salome Charalambous, Joseph Mendy, Isatou C. M. Sey, Abhishek Bakuli, Andrea Rachow, Christof Geldmacher, Jayne S. Sutherland
Formato: article
Lenguaje:EN
Publicado: Frontiers Media S.A. 2021
Materias:
tuberculosis
neutrophils
myeloperoxidase
S100A8/9
MMP8
lung pathology
Immunologic diseases. Allergy
RC581-607
Acceso en línea:https://doaj.org/article/0c7071691b8a419991d0a4a023eb58fa
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