Extraction, Isolation and Characterization of Bioactive Compounds from <i>Artemisia</i> and Their Biological Significance: A Review

Diverse medicinal plants such as those from the genus <i>Artemisia</i> have been employed globally for centuries by individuals belonging to different cultures. Universally, <i>Artemisia</i> species have been used to remedy various maladies that range from simple fevers to ma...

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Autores principales: Rosemary Anibogwu, Karl De Jesus, Samjhana Pradhan, Srinath Pashikanti, Sameena Mateen, Kavita Sharma
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Publicado: MDPI AG 2021
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spelling oai:doaj.org-article:0c779739e65e4e54ad760f4606fe6fc22021-11-25T18:28:59ZExtraction, Isolation and Characterization of Bioactive Compounds from <i>Artemisia</i> and Their Biological Significance: A Review10.3390/molecules262269951420-3049https://doaj.org/article/0c779739e65e4e54ad760f4606fe6fc22021-11-01T00:00:00Zhttps://www.mdpi.com/1420-3049/26/22/6995https://doaj.org/toc/1420-3049Diverse medicinal plants such as those from the genus <i>Artemisia</i> have been employed globally for centuries by individuals belonging to different cultures. Universally, <i>Artemisia</i> species have been used to remedy various maladies that range from simple fevers to malaria. A survey conducted by the World Health Organization (WHO) demonstrated that 80% of the global population is highly reliant on herbal medicine for their primary healthcare. WHO recommends artemisinin-based combination therapies (ACT) for the treatment of global diseases such as malaria. Artemisinin is a bioactive compound derived from <i>Artemisia annua</i> leaves. It is a sesquiterpene endoperoxide with potent antimalarial properties. This review strives to instill natural products to chemists and others in diverse fields with a heterogeneous set of knowledge compiled from multifaceted researchers and organizations in literature. In particular, the various <i>Artemisia</i> species and effective extraction, isolation, and characterization methodologies are discussed in detail. An in-depth investigation into the literature reveals that divergent species of <i>Artemisia</i> exhibit a vast array of biological activities such as antimalarial, antitumor, and anti-inflammatory activities. There is substantial potential for bioactive compounds from <i>Artemisia</i> to provide significant relief from differing human ailments, but more meticulous research in this field is needed.Rosemary AnibogwuKarl De JesusSamjhana PradhanSrinath PashikantiSameena MateenKavita SharmaMDPI AGarticle<i>Artemisia</i>extractionisolationbioactive compoundsbiological activityOrganic chemistryQD241-441ENMolecules, Vol 26, Iss 6995, p 6995 (2021)
institution DOAJ
collection DOAJ
language EN
topic <i>Artemisia</i>
extraction
isolation
bioactive compounds
biological activity
Organic chemistry
QD241-441
spellingShingle <i>Artemisia</i>
extraction
isolation
bioactive compounds
biological activity
Organic chemistry
QD241-441
Rosemary Anibogwu
Karl De Jesus
Samjhana Pradhan
Srinath Pashikanti
Sameena Mateen
Kavita Sharma
Extraction, Isolation and Characterization of Bioactive Compounds from <i>Artemisia</i> and Their Biological Significance: A Review
description Diverse medicinal plants such as those from the genus <i>Artemisia</i> have been employed globally for centuries by individuals belonging to different cultures. Universally, <i>Artemisia</i> species have been used to remedy various maladies that range from simple fevers to malaria. A survey conducted by the World Health Organization (WHO) demonstrated that 80% of the global population is highly reliant on herbal medicine for their primary healthcare. WHO recommends artemisinin-based combination therapies (ACT) for the treatment of global diseases such as malaria. Artemisinin is a bioactive compound derived from <i>Artemisia annua</i> leaves. It is a sesquiterpene endoperoxide with potent antimalarial properties. This review strives to instill natural products to chemists and others in diverse fields with a heterogeneous set of knowledge compiled from multifaceted researchers and organizations in literature. In particular, the various <i>Artemisia</i> species and effective extraction, isolation, and characterization methodologies are discussed in detail. An in-depth investigation into the literature reveals that divergent species of <i>Artemisia</i> exhibit a vast array of biological activities such as antimalarial, antitumor, and anti-inflammatory activities. There is substantial potential for bioactive compounds from <i>Artemisia</i> to provide significant relief from differing human ailments, but more meticulous research in this field is needed.
format article
author Rosemary Anibogwu
Karl De Jesus
Samjhana Pradhan
Srinath Pashikanti
Sameena Mateen
Kavita Sharma
author_facet Rosemary Anibogwu
Karl De Jesus
Samjhana Pradhan
Srinath Pashikanti
Sameena Mateen
Kavita Sharma
author_sort Rosemary Anibogwu
title Extraction, Isolation and Characterization of Bioactive Compounds from <i>Artemisia</i> and Their Biological Significance: A Review
title_short Extraction, Isolation and Characterization of Bioactive Compounds from <i>Artemisia</i> and Their Biological Significance: A Review
title_full Extraction, Isolation and Characterization of Bioactive Compounds from <i>Artemisia</i> and Their Biological Significance: A Review
title_fullStr Extraction, Isolation and Characterization of Bioactive Compounds from <i>Artemisia</i> and Their Biological Significance: A Review
title_full_unstemmed Extraction, Isolation and Characterization of Bioactive Compounds from <i>Artemisia</i> and Their Biological Significance: A Review
title_sort extraction, isolation and characterization of bioactive compounds from <i>artemisia</i> and their biological significance: a review
publisher MDPI AG
publishDate 2021
url https://doaj.org/article/0c779739e65e4e54ad760f4606fe6fc2
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