A steric gate controls P/E hybrid-state formation of tRNA on the ribosome
The ribosome undergoes multiple large-scale structural rearrangements during protein elongation. Here the authors present an all-atom model of the ribosome to study the energetics of P/E hybrid-state formation, an early conformational rearrangement occurring during translocation.
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Autores principales: | Mariana Levi, Kelsey Walak, Ailun Wang, Udayan Mohanty, Paul C. Whitford |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2020
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Materias: | |
Acceso en línea: | https://doaj.org/article/0c77e490ee1d488495d31d990f104c0c |
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