TRAIL regulatory receptors constrain human hepatic stellate cell apoptosis
Abstract The TRAIL pathway can mediate apoptosis of hepatic stellate cells to promote the resolution of liver fibrosis. However, TRAIL has the capacity to bind to regulatory receptors in addition to death-inducing receptors; their differential roles in liver fibrosis have not been investigated. Here...
Guardado en:
Autores principales: | Harsimran D. Singh, Itziar Otano, Krista Rombouts, Kasha P. Singh, Dimitra Peppa, Upkar S. Gill, Katrin Böttcher, Patrick T. F. Kennedy, Jude Oben, Massimo Pinzani, Henning Walczak, Giuseppe Fusai, William M. C. Rosenberg, Mala K. Maini |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
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Materias: | |
Acceso en línea: | https://doaj.org/article/0c84e0f5a1504bfe85b9a7ea0c3a5f5a |
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