Risk factors for polypharmacy in older adults in a primary care setting: a cross-sectional study

Suleyman Ersoy,1 Velittin Selcuk Engin2 1Department of Family Medicine, Faculty of Medicine, Karabuk University, Karabuk, Turkey; 2Melekhatun Family Practice Center, Ministry of Health, Istanbul 34340, Turkey Purpose: Polypharmacy (PP) is a clinical challenge in older adults. Therefore, assessment...

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Autores principales:	Ersoy S, Engin VS
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2018
Materias:	Polypharmacy older adult primary care Geriatric Depression Scale metabolic syndrome neutrophil/lymphocyte ratio Geriatrics RC952-954.6
Acceso en línea:	https://doaj.org/article/0c884f47c25e4ee4b21e4452c056f632
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spelling	oai:doaj.org-article:0c884f47c25e4ee4b21e4452c056f6322021-12-02T03:53:52ZRisk factors for polypharmacy in older adults in a primary care setting: a cross-sectional study1178-1998https://doaj.org/article/0c884f47c25e4ee4b21e4452c056f6322018-10-01T00:00:00Zhttps://www.dovepress.com/risk-factors-for-polypharmacy-in-older-adults-in-a-primary-care-settin-peer-reviewed-article-CIAhttps://doaj.org/toc/1178-1998Suleyman Ersoy,1 Velittin Selcuk Engin2 1Department of Family Medicine, Faculty of Medicine, Karabuk University, Karabuk, Turkey; 2Melekhatun Family Practice Center, Ministry of Health, Istanbul 34340, Turkey Purpose: Polypharmacy (PP) is a clinical challenge in older adults. Therefore, assessment of daily drug consumption (DDC) and its relationships is important. First-line health services have a crucial role in monitoring and preventing PP. In this study, we aimed to assess DDC and investigate the risk factors for higher DDC among older adults in a primary care setting.Patients and methods: A total of 1,000 patients aged ≥65 years who visited Melek Hatun Family Practice Center between December 1, 2014, and August 1, 2017, were enrolled in the study. All patients were seen either at the center or in their homes, and informed consent was obtained. Comprehensive geriatric assessment was performed for each subject. Data were analyzed using SPSS software (version 17). The daily number of medicines that each patient used (DDC) regardless of whether they were prescribed was the dependent variable. Relationships between DDC and other continuous variables were examined using Pearson’s correlation. For between-group comparisons of DDC, Student’s t-tests were performed.Results: Univariate tests showed relationships between DDC and various demographic and clinical parameters. The variables that remained significant at the last step of a stepwise linear regression analysis were metabolic syndrome, chronic pain, incontinence, increased serum creatinine level, increased Geriatric Depression Scale scores, reported gastric disturbances, and neutrophil/lymphocyte ratio.Conclusion: Along with certain chronic conditions, depressive symptoms and an inflammatory marker (neutrophil/lymphocyte ratio) were significantly and independently related to higher DDC. Longitudinal and larger studies are needed to further explore the multifaceted relationships of PP. Keywords: polypharmacy, older adult, primary care, Geriatric Depression Scale, metabolic syndrome, neutrophil/lymphocyte ratioErsoy SEngin VSDove Medical PressarticlePolypharmacyolder adultprimary careGeriatric Depression Scalemetabolic syndromeneutrophil/lymphocyte ratioGeriatricsRC952-954.6ENClinical Interventions in Aging, Vol Volume 13, Pp 2003-2011 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Polypharmacy older adult primary care Geriatric Depression Scale metabolic syndrome neutrophil/lymphocyte ratio Geriatrics RC952-954.6
spellingShingle	Polypharmacy older adult primary care Geriatric Depression Scale metabolic syndrome neutrophil/lymphocyte ratio Geriatrics RC952-954.6 Ersoy S Engin VS Risk factors for polypharmacy in older adults in a primary care setting: a cross-sectional study
description	Suleyman Ersoy,1 Velittin Selcuk Engin2 1Department of Family Medicine, Faculty of Medicine, Karabuk University, Karabuk, Turkey; 2Melekhatun Family Practice Center, Ministry of Health, Istanbul 34340, Turkey Purpose: Polypharmacy (PP) is a clinical challenge in older adults. Therefore, assessment of daily drug consumption (DDC) and its relationships is important. First-line health services have a crucial role in monitoring and preventing PP. In this study, we aimed to assess DDC and investigate the risk factors for higher DDC among older adults in a primary care setting.Patients and methods: A total of 1,000 patients aged ≥65 years who visited Melek Hatun Family Practice Center between December 1, 2014, and August 1, 2017, were enrolled in the study. All patients were seen either at the center or in their homes, and informed consent was obtained. Comprehensive geriatric assessment was performed for each subject. Data were analyzed using SPSS software (version 17). The daily number of medicines that each patient used (DDC) regardless of whether they were prescribed was the dependent variable. Relationships between DDC and other continuous variables were examined using Pearson’s correlation. For between-group comparisons of DDC, Student’s t-tests were performed.Results: Univariate tests showed relationships between DDC and various demographic and clinical parameters. The variables that remained significant at the last step of a stepwise linear regression analysis were metabolic syndrome, chronic pain, incontinence, increased serum creatinine level, increased Geriatric Depression Scale scores, reported gastric disturbances, and neutrophil/lymphocyte ratio.Conclusion: Along with certain chronic conditions, depressive symptoms and an inflammatory marker (neutrophil/lymphocyte ratio) were significantly and independently related to higher DDC. Longitudinal and larger studies are needed to further explore the multifaceted relationships of PP. Keywords: polypharmacy, older adult, primary care, Geriatric Depression Scale, metabolic syndrome, neutrophil/lymphocyte ratio
format	article
author	Ersoy S Engin VS
author_facet	Ersoy S Engin VS
author_sort	Ersoy S
title	Risk factors for polypharmacy in older adults in a primary care setting: a cross-sectional study
title_short	Risk factors for polypharmacy in older adults in a primary care setting: a cross-sectional study
title_full	Risk factors for polypharmacy in older adults in a primary care setting: a cross-sectional study
title_fullStr	Risk factors for polypharmacy in older adults in a primary care setting: a cross-sectional study
title_full_unstemmed	Risk factors for polypharmacy in older adults in a primary care setting: a cross-sectional study
title_sort	risk factors for polypharmacy in older adults in a primary care setting: a cross-sectional study
publisher	Dove Medical Press
publishDate	2018
url	https://doaj.org/article/0c884f47c25e4ee4b21e4452c056f632
work_keys_str_mv	AT ersoys riskfactorsforpolypharmacyinolderadultsinaprimarycaresettingacrosssectionalstudy AT enginvs riskfactorsforpolypharmacyinolderadultsinaprimarycaresettingacrosssectionalstudy
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Risk factors for polypharmacy in older adults in a primary care setting: a cross-sectional study

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