MRAP2 regulates ghrelin receptor signaling and hunger sensing
Melanocortin receptor accessory protein 2 (MRAP2) is an adaptor protein that contributes to melanocortin-4 receptor and prokineticin receptor 1 signalling. Here the authors show that MRAP2 also regulates ghrelin receptor signalling in the hypothalamus and starvation sensing in mice.
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Nature Portfolio
2017
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oai:doaj.org-article:0c8ac5f69f6445bd9e9a8456fe6f8bef2021-12-02T14:42:18ZMRAP2 regulates ghrelin receptor signaling and hunger sensing10.1038/s41467-017-00747-62041-1723https://doaj.org/article/0c8ac5f69f6445bd9e9a8456fe6f8bef2017-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-00747-6https://doaj.org/toc/2041-1723Melanocortin receptor accessory protein 2 (MRAP2) is an adaptor protein that contributes to melanocortin-4 receptor and prokineticin receptor 1 signalling. Here the authors show that MRAP2 also regulates ghrelin receptor signalling in the hypothalamus and starvation sensing in mice.Dollada SrisaiTerry C. YinAbigail A. LeeAlix A. J. RouaultNicole A. PearsonJustin L. GrobeJulien A. SebagNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-10 (2017) |
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EN |
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Science Q |
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Science Q Dollada Srisai Terry C. Yin Abigail A. Lee Alix A. J. Rouault Nicole A. Pearson Justin L. Grobe Julien A. Sebag MRAP2 regulates ghrelin receptor signaling and hunger sensing |
description |
Melanocortin receptor accessory protein 2 (MRAP2) is an adaptor protein that contributes to melanocortin-4 receptor and prokineticin receptor 1 signalling. Here the authors show that MRAP2 also regulates ghrelin receptor signalling in the hypothalamus and starvation sensing in mice. |
format |
article |
author |
Dollada Srisai Terry C. Yin Abigail A. Lee Alix A. J. Rouault Nicole A. Pearson Justin L. Grobe Julien A. Sebag |
author_facet |
Dollada Srisai Terry C. Yin Abigail A. Lee Alix A. J. Rouault Nicole A. Pearson Justin L. Grobe Julien A. Sebag |
author_sort |
Dollada Srisai |
title |
MRAP2 regulates ghrelin receptor signaling and hunger sensing |
title_short |
MRAP2 regulates ghrelin receptor signaling and hunger sensing |
title_full |
MRAP2 regulates ghrelin receptor signaling and hunger sensing |
title_fullStr |
MRAP2 regulates ghrelin receptor signaling and hunger sensing |
title_full_unstemmed |
MRAP2 regulates ghrelin receptor signaling and hunger sensing |
title_sort |
mrap2 regulates ghrelin receptor signaling and hunger sensing |
publisher |
Nature Portfolio |
publishDate |
2017 |
url |
https://doaj.org/article/0c8ac5f69f6445bd9e9a8456fe6f8bef |
work_keys_str_mv |
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_version_ |
1718389733143347200 |