MRAP2 regulates ghrelin receptor signaling and hunger sensing

Melanocortin receptor accessory protein 2 (MRAP2) is an adaptor protein that contributes to melanocortin-4 receptor and prokineticin receptor 1 signalling. Here the authors show that MRAP2 also regulates ghrelin receptor signalling in the hypothalamus and starvation sensing in mice.

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Autores principales: Dollada Srisai, Terry C. Yin, Abigail A. Lee, Alix A. J. Rouault, Nicole A. Pearson, Justin L. Grobe, Julien A. Sebag
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/0c8ac5f69f6445bd9e9a8456fe6f8bef
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spelling oai:doaj.org-article:0c8ac5f69f6445bd9e9a8456fe6f8bef2021-12-02T14:42:18ZMRAP2 regulates ghrelin receptor signaling and hunger sensing10.1038/s41467-017-00747-62041-1723https://doaj.org/article/0c8ac5f69f6445bd9e9a8456fe6f8bef2017-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-00747-6https://doaj.org/toc/2041-1723Melanocortin receptor accessory protein 2 (MRAP2) is an adaptor protein that contributes to melanocortin-4 receptor and prokineticin receptor 1 signalling. Here the authors show that MRAP2 also regulates ghrelin receptor signalling in the hypothalamus and starvation sensing in mice.Dollada SrisaiTerry C. YinAbigail A. LeeAlix A. J. RouaultNicole A. PearsonJustin L. GrobeJulien A. SebagNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Dollada Srisai
Terry C. Yin
Abigail A. Lee
Alix A. J. Rouault
Nicole A. Pearson
Justin L. Grobe
Julien A. Sebag
MRAP2 regulates ghrelin receptor signaling and hunger sensing
description Melanocortin receptor accessory protein 2 (MRAP2) is an adaptor protein that contributes to melanocortin-4 receptor and prokineticin receptor 1 signalling. Here the authors show that MRAP2 also regulates ghrelin receptor signalling in the hypothalamus and starvation sensing in mice.
format article
author Dollada Srisai
Terry C. Yin
Abigail A. Lee
Alix A. J. Rouault
Nicole A. Pearson
Justin L. Grobe
Julien A. Sebag
author_facet Dollada Srisai
Terry C. Yin
Abigail A. Lee
Alix A. J. Rouault
Nicole A. Pearson
Justin L. Grobe
Julien A. Sebag
author_sort Dollada Srisai
title MRAP2 regulates ghrelin receptor signaling and hunger sensing
title_short MRAP2 regulates ghrelin receptor signaling and hunger sensing
title_full MRAP2 regulates ghrelin receptor signaling and hunger sensing
title_fullStr MRAP2 regulates ghrelin receptor signaling and hunger sensing
title_full_unstemmed MRAP2 regulates ghrelin receptor signaling and hunger sensing
title_sort mrap2 regulates ghrelin receptor signaling and hunger sensing
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/0c8ac5f69f6445bd9e9a8456fe6f8bef
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