MRAP2 regulates ghrelin receptor signaling and hunger sensing
Melanocortin receptor accessory protein 2 (MRAP2) is an adaptor protein that contributes to melanocortin-4 receptor and prokineticin receptor 1 signalling. Here the authors show that MRAP2 also regulates ghrelin receptor signalling in the hypothalamus and starvation sensing in mice.
Guardado en:
Autores principales: | Dollada Srisai, Terry C. Yin, Abigail A. Lee, Alix A. J. Rouault, Nicole A. Pearson, Justin L. Grobe, Julien A. Sebag |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
|
Materias: | |
Acceso en línea: | https://doaj.org/article/0c8ac5f69f6445bd9e9a8456fe6f8bef |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Structural basis of human ghrelin receptor signaling by ghrelin and the synthetic agonist ibutamoren
por: Heng Liu, et al.
Publicado: (2021) -
Allosteric modulation of ghrelin receptor signaling by lipids
por: Marjorie Damian, et al.
Publicado: (2021) -
Structure of an antagonist-bound ghrelin receptor reveals possible ghrelin recognition mode
por: Yuki Shiimura, et al.
Publicado: (2020) -
Molecular recognition of an acyl-peptide hormone and activation of ghrelin receptor
por: Yue Wang, et al.
Publicado: (2021) -
Sensing of fatty acids for octanoylation of ghrelin involves a gustatory G-protein.
por: Sara Janssen, et al.
Publicado: (2012)