The real seroprevalence of SARS-CoV-2 in France and its consequences for virus dynamics

Abstract The SARS-CoV-2 virus has spread world-wide since December 2019, killing more than 2.9 million of people. We have adapted a statistical model from the SIR epidemiological models to predict the spread of SARS-CoV-2 in France. Our model is based on several parameters and assumed a 4.2% seropre...

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Autores principales: Chloé Dimeglio, Jean-Michel Loubes, Marcel Miedougé, Fabrice Herin, Jean-Marc Soulat, Jacques Izopet
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Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/0c8e3153d844405baaa3d65b65d428d9
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spelling oai:doaj.org-article:0c8e3153d844405baaa3d65b65d428d92021-12-02T17:23:47ZThe real seroprevalence of SARS-CoV-2 in France and its consequences for virus dynamics10.1038/s41598-021-92131-02045-2322https://doaj.org/article/0c8e3153d844405baaa3d65b65d428d92021-06-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-92131-0https://doaj.org/toc/2045-2322Abstract The SARS-CoV-2 virus has spread world-wide since December 2019, killing more than 2.9 million of people. We have adapted a statistical model from the SIR epidemiological models to predict the spread of SARS-CoV-2 in France. Our model is based on several parameters and assumed a 4.2% seroprevalence in Occitania after the first lockdown. The recent use of serological tests to measure the effective seroprevalence of SARS-CoV-2 in the population of Occitania has led to a seroprevalence around 2.4%. This implies to review the parameters of our model to conclude at a lower than expected virus transmission rate, which may be due to infectivity varying with the patient’s symptoms or to a constraint due to an uneven population geographical distribution.Chloé DimeglioJean-Michel LoubesMarcel MiedougéFabrice HerinJean-Marc SoulatJacques IzopetNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-5 (2021)
institution DOAJ
collection DOAJ
language EN
topic Medicine
R
Science
Q
spellingShingle Medicine
R
Science
Q
Chloé Dimeglio
Jean-Michel Loubes
Marcel Miedougé
Fabrice Herin
Jean-Marc Soulat
Jacques Izopet
The real seroprevalence of SARS-CoV-2 in France and its consequences for virus dynamics
description Abstract The SARS-CoV-2 virus has spread world-wide since December 2019, killing more than 2.9 million of people. We have adapted a statistical model from the SIR epidemiological models to predict the spread of SARS-CoV-2 in France. Our model is based on several parameters and assumed a 4.2% seroprevalence in Occitania after the first lockdown. The recent use of serological tests to measure the effective seroprevalence of SARS-CoV-2 in the population of Occitania has led to a seroprevalence around 2.4%. This implies to review the parameters of our model to conclude at a lower than expected virus transmission rate, which may be due to infectivity varying with the patient’s symptoms or to a constraint due to an uneven population geographical distribution.
format article
author Chloé Dimeglio
Jean-Michel Loubes
Marcel Miedougé
Fabrice Herin
Jean-Marc Soulat
Jacques Izopet
author_facet Chloé Dimeglio
Jean-Michel Loubes
Marcel Miedougé
Fabrice Herin
Jean-Marc Soulat
Jacques Izopet
author_sort Chloé Dimeglio
title The real seroprevalence of SARS-CoV-2 in France and its consequences for virus dynamics
title_short The real seroprevalence of SARS-CoV-2 in France and its consequences for virus dynamics
title_full The real seroprevalence of SARS-CoV-2 in France and its consequences for virus dynamics
title_fullStr The real seroprevalence of SARS-CoV-2 in France and its consequences for virus dynamics
title_full_unstemmed The real seroprevalence of SARS-CoV-2 in France and its consequences for virus dynamics
title_sort real seroprevalence of sars-cov-2 in france and its consequences for virus dynamics
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/0c8e3153d844405baaa3d65b65d428d9
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