Imaging tumour cell heterogeneity following cell transplantation into optically clear immune-deficient zebrafish

Direct visualisation of heterogeneous cell populations in live animals has been challenging. Here, the authors optimize cell transplantation into optically clear immune-deficient zebrafish, and use intravital imaging to track and to assess functional diversity of individual cancer cells in vivo.

Guardado en:

Detalles Bibliográficos
Autores principales:	Qin Tang, John C. Moore, Myron S. Ignatius, Inês M. Tenente, Madeline N. Hayes, Elaine G. Garcia, Nora Torres Yordán, Caitlin Bourque, Shuning He, Jessica S. Blackburn, A. Thomas Look, Yariv Houvras, David M. Langenau
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/0c91eceedf1044eca16d9570f08e6ec0
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:0c91eceedf1044eca16d9570f08e6ec0
record_format	dspace
spelling	oai:doaj.org-article:0c91eceedf1044eca16d9570f08e6ec02021-12-02T15:33:47ZImaging tumour cell heterogeneity following cell transplantation into optically clear immune-deficient zebrafish10.1038/ncomms103582041-1723https://doaj.org/article/0c91eceedf1044eca16d9570f08e6ec02016-01-01T00:00:00Zhttps://doi.org/10.1038/ncomms10358https://doaj.org/toc/2041-1723Direct visualisation of heterogeneous cell populations in live animals has been challenging. Here, the authors optimize cell transplantation into optically clear immune-deficient zebrafish, and use intravital imaging to track and to assess functional diversity of individual cancer cells in vivo.Qin TangJohn C. MooreMyron S. IgnatiusInês M. TenenteMadeline N. HayesElaine G. GarciaNora Torres YordánCaitlin BourqueShuning HeJessica S. BlackburnA. Thomas LookYariv HouvrasDavid M. LangenauNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Qin Tang John C. Moore Myron S. Ignatius Inês M. Tenente Madeline N. Hayes Elaine G. Garcia Nora Torres Yordán Caitlin Bourque Shuning He Jessica S. Blackburn A. Thomas Look Yariv Houvras David M. Langenau Imaging tumour cell heterogeneity following cell transplantation into optically clear immune-deficient zebrafish
description	Direct visualisation of heterogeneous cell populations in live animals has been challenging. Here, the authors optimize cell transplantation into optically clear immune-deficient zebrafish, and use intravital imaging to track and to assess functional diversity of individual cancer cells in vivo.
format	article
author	Qin Tang John C. Moore Myron S. Ignatius Inês M. Tenente Madeline N. Hayes Elaine G. Garcia Nora Torres Yordán Caitlin Bourque Shuning He Jessica S. Blackburn A. Thomas Look Yariv Houvras David M. Langenau
author_facet	Qin Tang John C. Moore Myron S. Ignatius Inês M. Tenente Madeline N. Hayes Elaine G. Garcia Nora Torres Yordán Caitlin Bourque Shuning He Jessica S. Blackburn A. Thomas Look Yariv Houvras David M. Langenau
author_sort	Qin Tang
title	Imaging tumour cell heterogeneity following cell transplantation into optically clear immune-deficient zebrafish
title_short	Imaging tumour cell heterogeneity following cell transplantation into optically clear immune-deficient zebrafish
title_full	Imaging tumour cell heterogeneity following cell transplantation into optically clear immune-deficient zebrafish
title_fullStr	Imaging tumour cell heterogeneity following cell transplantation into optically clear immune-deficient zebrafish
title_full_unstemmed	Imaging tumour cell heterogeneity following cell transplantation into optically clear immune-deficient zebrafish
title_sort	imaging tumour cell heterogeneity following cell transplantation into optically clear immune-deficient zebrafish
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/0c91eceedf1044eca16d9570f08e6ec0
work_keys_str_mv	AT qintang imagingtumourcellheterogeneityfollowingcelltransplantationintoopticallyclearimmunedeficientzebrafish AT johncmoore imagingtumourcellheterogeneityfollowingcelltransplantationintoopticallyclearimmunedeficientzebrafish AT myronsignatius imagingtumourcellheterogeneityfollowingcelltransplantationintoopticallyclearimmunedeficientzebrafish AT inesmtenente imagingtumourcellheterogeneityfollowingcelltransplantationintoopticallyclearimmunedeficientzebrafish AT madelinenhayes imagingtumourcellheterogeneityfollowingcelltransplantationintoopticallyclearimmunedeficientzebrafish AT elaineggarcia imagingtumourcellheterogeneityfollowingcelltransplantationintoopticallyclearimmunedeficientzebrafish AT noratorresyordan imagingtumourcellheterogeneityfollowingcelltransplantationintoopticallyclearimmunedeficientzebrafish AT caitlinbourque imagingtumourcellheterogeneityfollowingcelltransplantationintoopticallyclearimmunedeficientzebrafish AT shuninghe imagingtumourcellheterogeneityfollowingcelltransplantationintoopticallyclearimmunedeficientzebrafish AT jessicasblackburn imagingtumourcellheterogeneityfollowingcelltransplantationintoopticallyclearimmunedeficientzebrafish AT athomaslook imagingtumourcellheterogeneityfollowingcelltransplantationintoopticallyclearimmunedeficientzebrafish AT yarivhouvras imagingtumourcellheterogeneityfollowingcelltransplantationintoopticallyclearimmunedeficientzebrafish AT davidmlangenau imagingtumourcellheterogeneityfollowingcelltransplantationintoopticallyclearimmunedeficientzebrafish
_version_	1718387004590260224

Imaging tumour cell heterogeneity following cell transplantation into optically clear immune-deficient zebrafish

Ejemplares similares