Elimination of HIV-1-infected cells by broadly neutralizing antibodies

Broadly neutralizing antibodies (bNAbs) are promising as potential therapies targeting HIV-1 but their overall antiviral activity remains to be fully elucidated. Here the authors evaluate the ability of a panel of bNAbs to trigger antibody-dependent cellular cytotoxicity and identify the most effect...

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Autores principales:	Timothée Bruel, Florence Guivel-Benhassine, Sonia Amraoui, Marine Malbec, Léa Richard, Katia Bourdic, Daniel Aaron Donahue, Valérie Lorin, Nicoletta Casartelli, Nicolas Noël, Olivier Lambotte, Hugo Mouquet, Olivier Schwartz
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/0c92443559f14621a72a3877677ac63a
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spelling	oai:doaj.org-article:0c92443559f14621a72a3877677ac63a2021-12-02T15:35:20ZElimination of HIV-1-infected cells by broadly neutralizing antibodies10.1038/ncomms108442041-1723https://doaj.org/article/0c92443559f14621a72a3877677ac63a2016-03-01T00:00:00Zhttps://doi.org/10.1038/ncomms10844https://doaj.org/toc/2041-1723Broadly neutralizing antibodies (bNAbs) are promising as potential therapies targeting HIV-1 but their overall antiviral activity remains to be fully elucidated. Here the authors evaluate the ability of a panel of bNAbs to trigger antibody-dependent cellular cytotoxicity and identify the most effective antibody combinations.Timothée BruelFlorence Guivel-BenhassineSonia AmraouiMarine MalbecLéa RichardKatia BourdicDaniel Aaron DonahueValérie LorinNicoletta CasartelliNicolas NoëlOlivier LambotteHugo MouquetOlivier SchwartzNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Timothée Bruel Florence Guivel-Benhassine Sonia Amraoui Marine Malbec Léa Richard Katia Bourdic Daniel Aaron Donahue Valérie Lorin Nicoletta Casartelli Nicolas Noël Olivier Lambotte Hugo Mouquet Olivier Schwartz Elimination of HIV-1-infected cells by broadly neutralizing antibodies
description	Broadly neutralizing antibodies (bNAbs) are promising as potential therapies targeting HIV-1 but their overall antiviral activity remains to be fully elucidated. Here the authors evaluate the ability of a panel of bNAbs to trigger antibody-dependent cellular cytotoxicity and identify the most effective antibody combinations.
format	article
author	Timothée Bruel Florence Guivel-Benhassine Sonia Amraoui Marine Malbec Léa Richard Katia Bourdic Daniel Aaron Donahue Valérie Lorin Nicoletta Casartelli Nicolas Noël Olivier Lambotte Hugo Mouquet Olivier Schwartz
author_facet	Timothée Bruel Florence Guivel-Benhassine Sonia Amraoui Marine Malbec Léa Richard Katia Bourdic Daniel Aaron Donahue Valérie Lorin Nicoletta Casartelli Nicolas Noël Olivier Lambotte Hugo Mouquet Olivier Schwartz
author_sort	Timothée Bruel
title	Elimination of HIV-1-infected cells by broadly neutralizing antibodies
title_short	Elimination of HIV-1-infected cells by broadly neutralizing antibodies
title_full	Elimination of HIV-1-infected cells by broadly neutralizing antibodies
title_fullStr	Elimination of HIV-1-infected cells by broadly neutralizing antibodies
title_full_unstemmed	Elimination of HIV-1-infected cells by broadly neutralizing antibodies
title_sort	elimination of hiv-1-infected cells by broadly neutralizing antibodies
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/0c92443559f14621a72a3877677ac63a
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Elimination of HIV-1-infected cells by broadly neutralizing antibodies

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