Multimodal interference-based imaging of nanoscale structure and macromolecular motion uncovers UV induced cellular paroxysm

Methods to track molecular motion in eukaryotic cells mostly rely on fluorescent labels, transfection or photobleaching. Here the authors use multimodal partial wave spectroscopy to perform label-free live cell measurements of nanoscale structure and macromolecular motion with millisecond temporal r...

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Autores principales:	Scott Gladstein, Luay M. Almassalha, Lusik Cherkezyan, John E. Chandler, Adam Eshein, Aya Eid, Di Zhang, Wenli Wu, Greta M. Bauer, Andrew D. Stephens, Simona Morochnik, Hariharan Subramanian, John F. Marko, Guillermo A. Ameer, Igal Szleifer, Vadim Backman
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/0c957e1c9b824bd39ac73359f6e497aa
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spelling	oai:doaj.org-article:0c957e1c9b824bd39ac73359f6e497aa2021-12-02T15:35:15ZMultimodal interference-based imaging of nanoscale structure and macromolecular motion uncovers UV induced cellular paroxysm10.1038/s41467-019-09717-62041-1723https://doaj.org/article/0c957e1c9b824bd39ac73359f6e497aa2019-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-09717-6https://doaj.org/toc/2041-1723Methods to track molecular motion in eukaryotic cells mostly rely on fluorescent labels, transfection or photobleaching. Here the authors use multimodal partial wave spectroscopy to perform label-free live cell measurements of nanoscale structure and macromolecular motion with millisecond temporal resolution.Scott GladsteinLuay M. AlmassalhaLusik CherkezyanJohn E. ChandlerAdam EsheinAya EidDi ZhangWenli WuGreta M. BauerAndrew D. StephensSimona MorochnikHariharan SubramanianJohn F. MarkoGuillermo A. AmeerIgal SzleiferVadim BackmanNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Scott Gladstein Luay M. Almassalha Lusik Cherkezyan John E. Chandler Adam Eshein Aya Eid Di Zhang Wenli Wu Greta M. Bauer Andrew D. Stephens Simona Morochnik Hariharan Subramanian John F. Marko Guillermo A. Ameer Igal Szleifer Vadim Backman Multimodal interference-based imaging of nanoscale structure and macromolecular motion uncovers UV induced cellular paroxysm
description	Methods to track molecular motion in eukaryotic cells mostly rely on fluorescent labels, transfection or photobleaching. Here the authors use multimodal partial wave spectroscopy to perform label-free live cell measurements of nanoscale structure and macromolecular motion with millisecond temporal resolution.
format	article
author	Scott Gladstein Luay M. Almassalha Lusik Cherkezyan John E. Chandler Adam Eshein Aya Eid Di Zhang Wenli Wu Greta M. Bauer Andrew D. Stephens Simona Morochnik Hariharan Subramanian John F. Marko Guillermo A. Ameer Igal Szleifer Vadim Backman
author_facet	Scott Gladstein Luay M. Almassalha Lusik Cherkezyan John E. Chandler Adam Eshein Aya Eid Di Zhang Wenli Wu Greta M. Bauer Andrew D. Stephens Simona Morochnik Hariharan Subramanian John F. Marko Guillermo A. Ameer Igal Szleifer Vadim Backman
author_sort	Scott Gladstein
title	Multimodal interference-based imaging of nanoscale structure and macromolecular motion uncovers UV induced cellular paroxysm
title_short	Multimodal interference-based imaging of nanoscale structure and macromolecular motion uncovers UV induced cellular paroxysm
title_full	Multimodal interference-based imaging of nanoscale structure and macromolecular motion uncovers UV induced cellular paroxysm
title_fullStr	Multimodal interference-based imaging of nanoscale structure and macromolecular motion uncovers UV induced cellular paroxysm
title_full_unstemmed	Multimodal interference-based imaging of nanoscale structure and macromolecular motion uncovers UV induced cellular paroxysm
title_sort	multimodal interference-based imaging of nanoscale structure and macromolecular motion uncovers uv induced cellular paroxysm
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/0c957e1c9b824bd39ac73359f6e497aa
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Multimodal interference-based imaging of nanoscale structure and macromolecular motion uncovers UV induced cellular paroxysm

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