Scalable visible light 3D printing and bioprinting using an organic light-emitting diode microdisplay

Summary: To address current unmet needs in terms of scalability and material biocompatibility for future photocrosslinking-based additive manufacturing technologies, emergent platform designs are in inexorable demand. In particular, a shift from the present use of cell-damaging UV light sources in l...

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Autores principales:	Kavin Kowsari, Wonhye Lee, Seung-Schik Yoo, Nicholas Xuanlai Fang
Formato:	article
Lenguaje:	EN
Publicado:	Elsevier 2021
Materias:	Bioelectrochemistry Bioengineering Devices Science Q
Acceso en línea:	https://doaj.org/article/0c97d8ffac274d05966d8303b457442c
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spelling	oai:doaj.org-article:0c97d8ffac274d05966d8303b457442c2021-11-20T05:10:48ZScalable visible light 3D printing and bioprinting using an organic light-emitting diode microdisplay2589-004210.1016/j.isci.2021.103372https://doaj.org/article/0c97d8ffac274d05966d8303b457442c2021-11-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S2589004221013432https://doaj.org/toc/2589-0042Summary: To address current unmet needs in terms of scalability and material biocompatibility for future photocrosslinking-based additive manufacturing technologies, emergent platform designs are in inexorable demand. In particular, a shift from the present use of cell-damaging UV light sources in light-based three-dimensional (3D) bioprinting methods demands new platforms. We adopted an organic light-emitting diode (OLED) microdisplay as a digital visible light modulator to create a 3D printing platform modality that offers scalability and multi-material capability while forgoing the need for UV photocrosslinking. We formulate biocompatible inks that are visible light-crosslinkable with relatively quick photoinitiation rates. We demonstrated successful attachment and rapid growth of primary human dermal fibroblast-adult (HDF-a) cells on biological substrates fabricated using the OLED platform. This platform incites new possibilities by providing a simple-yet-effective means for low-cost, high-throughput, and multi-material 3D fabrication of functional structures made of polymers, ceramic composites, and biomaterials.Kavin KowsariWonhye LeeSeung-Schik YooNicholas Xuanlai FangElsevierarticleBioelectrochemistryBioengineeringDevicesScienceQENiScience, Vol 24, Iss 11, Pp 103372- (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Bioelectrochemistry Bioengineering Devices Science Q
spellingShingle	Bioelectrochemistry Bioengineering Devices Science Q Kavin Kowsari Wonhye Lee Seung-Schik Yoo Nicholas Xuanlai Fang Scalable visible light 3D printing and bioprinting using an organic light-emitting diode microdisplay
description	Summary: To address current unmet needs in terms of scalability and material biocompatibility for future photocrosslinking-based additive manufacturing technologies, emergent platform designs are in inexorable demand. In particular, a shift from the present use of cell-damaging UV light sources in light-based three-dimensional (3D) bioprinting methods demands new platforms. We adopted an organic light-emitting diode (OLED) microdisplay as a digital visible light modulator to create a 3D printing platform modality that offers scalability and multi-material capability while forgoing the need for UV photocrosslinking. We formulate biocompatible inks that are visible light-crosslinkable with relatively quick photoinitiation rates. We demonstrated successful attachment and rapid growth of primary human dermal fibroblast-adult (HDF-a) cells on biological substrates fabricated using the OLED platform. This platform incites new possibilities by providing a simple-yet-effective means for low-cost, high-throughput, and multi-material 3D fabrication of functional structures made of polymers, ceramic composites, and biomaterials.
format	article
author	Kavin Kowsari Wonhye Lee Seung-Schik Yoo Nicholas Xuanlai Fang
author_facet	Kavin Kowsari Wonhye Lee Seung-Schik Yoo Nicholas Xuanlai Fang
author_sort	Kavin Kowsari
title	Scalable visible light 3D printing and bioprinting using an organic light-emitting diode microdisplay
title_short	Scalable visible light 3D printing and bioprinting using an organic light-emitting diode microdisplay
title_full	Scalable visible light 3D printing and bioprinting using an organic light-emitting diode microdisplay
title_fullStr	Scalable visible light 3D printing and bioprinting using an organic light-emitting diode microdisplay
title_full_unstemmed	Scalable visible light 3D printing and bioprinting using an organic light-emitting diode microdisplay
title_sort	scalable visible light 3d printing and bioprinting using an organic light-emitting diode microdisplay
publisher	Elsevier
publishDate	2021
url	https://doaj.org/article/0c97d8ffac274d05966d8303b457442c
work_keys_str_mv	AT kavinkowsari scalablevisiblelight3dprintingandbioprintingusinganorganiclightemittingdiodemicrodisplay AT wonhyelee scalablevisiblelight3dprintingandbioprintingusinganorganiclightemittingdiodemicrodisplay AT seungschikyoo scalablevisiblelight3dprintingandbioprintingusinganorganiclightemittingdiodemicrodisplay AT nicholasxuanlaifang scalablevisiblelight3dprintingandbioprintingusinganorganiclightemittingdiodemicrodisplay
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Scalable visible light 3D printing and bioprinting using an organic light-emitting diode microdisplay

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