miR-9a modulates maintenance and ageing of Drosophila germline stem cells by limiting N-cadherin expression

In the Drosophila testis, ageing leads to loss of germline stem cells. Here, the authors show that, during ageing in Drosophila, miR-9a is upregulated in male germline stem cells and regulates their proliferation by targeting N-cadherin.

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Autores principales:	Yehonatan Epstein, Noam Perry, Marina Volin, Maayan Zohar-Fux, Rachel Braun, Lilach Porat-Kuperstein, Hila Toledano
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/0c9869733bd54454ab88c0c74b86801a
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spelling	oai:doaj.org-article:0c9869733bd54454ab88c0c74b86801a2021-12-02T17:06:15ZmiR-9a modulates maintenance and ageing of Drosophila germline stem cells by limiting N-cadherin expression10.1038/s41467-017-00485-92041-1723https://doaj.org/article/0c9869733bd54454ab88c0c74b86801a2017-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-00485-9https://doaj.org/toc/2041-1723In the Drosophila testis, ageing leads to loss of germline stem cells. Here, the authors show that, during ageing in Drosophila, miR-9a is upregulated in male germline stem cells and regulates their proliferation by targeting N-cadherin.Yehonatan EpsteinNoam PerryMarina VolinMaayan Zohar-FuxRachel BraunLilach Porat-KupersteinHila ToledanoNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-9 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Yehonatan Epstein Noam Perry Marina Volin Maayan Zohar-Fux Rachel Braun Lilach Porat-Kuperstein Hila Toledano miR-9a modulates maintenance and ageing of Drosophila germline stem cells by limiting N-cadherin expression
description	In the Drosophila testis, ageing leads to loss of germline stem cells. Here, the authors show that, during ageing in Drosophila, miR-9a is upregulated in male germline stem cells and regulates their proliferation by targeting N-cadherin.
format	article
author	Yehonatan Epstein Noam Perry Marina Volin Maayan Zohar-Fux Rachel Braun Lilach Porat-Kuperstein Hila Toledano
author_facet	Yehonatan Epstein Noam Perry Marina Volin Maayan Zohar-Fux Rachel Braun Lilach Porat-Kuperstein Hila Toledano
author_sort	Yehonatan Epstein
title	miR-9a modulates maintenance and ageing of Drosophila germline stem cells by limiting N-cadherin expression
title_short	miR-9a modulates maintenance and ageing of Drosophila germline stem cells by limiting N-cadherin expression
title_full	miR-9a modulates maintenance and ageing of Drosophila germline stem cells by limiting N-cadherin expression
title_fullStr	miR-9a modulates maintenance and ageing of Drosophila germline stem cells by limiting N-cadherin expression
title_full_unstemmed	miR-9a modulates maintenance and ageing of Drosophila germline stem cells by limiting N-cadherin expression
title_sort	mir-9a modulates maintenance and ageing of drosophila germline stem cells by limiting n-cadherin expression
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/0c9869733bd54454ab88c0c74b86801a
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miR-9a modulates maintenance and ageing of Drosophila germline stem cells by limiting N-cadherin expression

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