Exercise downregulates HIPK2 and HIPK2 inhibition protects against myocardial infarction

Exercise downregulates HIPK2 and HIPK2 inhibition protects against myocardial infarction

Background: Exercise can protect myocardial infarction (MI) and downregulate cardiac Homeodomain-Interacting Protein Kinase 2 (HIPK2). However, the role of HIPK2 in MI is unclear. Methods: HIPK2–/– mice and miR-222–/– rats, HIPK2 inhibitor (PKI1H) and adeno-associated virus serotype 9 (AAV9) carryin...

Full description

Saved in:
Bibliographic Details
Main Authors: Qiulian Zhou, Jiali Deng, Jianhua Yao, Jiaxin Song, Danni Meng, Yujiao Zhu, Minjun Xu, Yajun Liang, Jiahong Xu, Joost PG Sluijter, Junjie Xiao
Format: article
Language:EN
Published: Elsevier 2021
Subjects:
Exercise
Myocardial infarction
HIPK2
miR-222
Medicine
R
Medicine (General)
R5-920
Online Access:https://doaj.org/article/0ca37ec124dc49cdadbe6ad4e0e1f44c
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doaj.org/article/0ca37ec124dc49cdadbe6ad4e0e1f44c

Similar Items