Temporal dynamics of protein complex formation and dissociation during human cytomegalovirus infection
Here, Hashimoto et al. apply mass spectrometry-based thermal proximity coaggregation to characterize the temporal dynamics of virus-host protein-protein interactions during human cytomegalovirus (HCMV) infection, uncovering proviral functions including the internalization of the HCMV receptor integr...
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Nature Portfolio
2020
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oai:doaj.org-article:0ca7fdb5104842789dbc540fcee827b12021-12-02T15:39:18ZTemporal dynamics of protein complex formation and dissociation during human cytomegalovirus infection10.1038/s41467-020-14586-52041-1723https://doaj.org/article/0ca7fdb5104842789dbc540fcee827b12020-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-14586-5https://doaj.org/toc/2041-1723Here, Hashimoto et al. apply mass spectrometry-based thermal proximity coaggregation to characterize the temporal dynamics of virus-host protein-protein interactions during human cytomegalovirus (HCMV) infection, uncovering proviral functions including the internalization of the HCMV receptor integrin beta 1 with CD63.Yutaka HashimotoXinlei ShengLaura A. Murray-NergerIleana M. CristeaNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-20 (2020) |
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Science Q Yutaka Hashimoto Xinlei Sheng Laura A. Murray-Nerger Ileana M. Cristea Temporal dynamics of protein complex formation and dissociation during human cytomegalovirus infection |
description |
Here, Hashimoto et al. apply mass spectrometry-based thermal proximity coaggregation to characterize the temporal dynamics of virus-host protein-protein interactions during human cytomegalovirus (HCMV) infection, uncovering proviral functions including the internalization of the HCMV receptor integrin beta 1 with CD63. |
format |
article |
author |
Yutaka Hashimoto Xinlei Sheng Laura A. Murray-Nerger Ileana M. Cristea |
author_facet |
Yutaka Hashimoto Xinlei Sheng Laura A. Murray-Nerger Ileana M. Cristea |
author_sort |
Yutaka Hashimoto |
title |
Temporal dynamics of protein complex formation and dissociation during human cytomegalovirus infection |
title_short |
Temporal dynamics of protein complex formation and dissociation during human cytomegalovirus infection |
title_full |
Temporal dynamics of protein complex formation and dissociation during human cytomegalovirus infection |
title_fullStr |
Temporal dynamics of protein complex formation and dissociation during human cytomegalovirus infection |
title_full_unstemmed |
Temporal dynamics of protein complex formation and dissociation during human cytomegalovirus infection |
title_sort |
temporal dynamics of protein complex formation and dissociation during human cytomegalovirus infection |
publisher |
Nature Portfolio |
publishDate |
2020 |
url |
https://doaj.org/article/0ca7fdb5104842789dbc540fcee827b1 |
work_keys_str_mv |
AT yutakahashimoto temporaldynamicsofproteincomplexformationanddissociationduringhumancytomegalovirusinfection AT xinleisheng temporaldynamicsofproteincomplexformationanddissociationduringhumancytomegalovirusinfection AT lauraamurraynerger temporaldynamicsofproteincomplexformationanddissociationduringhumancytomegalovirusinfection AT ileanamcristea temporaldynamicsofproteincomplexformationanddissociationduringhumancytomegalovirusinfection |
_version_ |
1718385912924078080 |