Fine needle aspiration cytology of primary sphenoid sinus esthesioneuroblastoma metastatic to the skin

Esthesioneuroblastoma (ENB) is a rare tumor derived from olfactory neuroepithelium. ENB in a site outside of where olfactory epithelium exists is exceedingly rare with only five cases of ENB isolated to the sphenoid sinuses described in the literature to date. To the best of our knowledge, a skin me...

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Autores principales:	Josephine Akinfolarin, Tarek Jazaerly, Kia Jones, Maher Abu-Hamdan, Fulvio Lonardo, Adam Folbe, Tamar Giorgadze
Formato:	article
Lenguaje:	EN
Publicado:	Thieme Medical and Scientific Publishers Pvt. Ltd. 2012
Materias:	esthesioneuroblastoma metastasis skin Medicine R
Acceso en línea:	https://doaj.org/article/0cb62326d0574cfe9f331acaa469973c
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spelling	oai:doaj.org-article:0cb62326d0574cfe9f331acaa469973c2021-12-02T16:38:06ZFine needle aspiration cytology of primary sphenoid sinus esthesioneuroblastoma metastatic to the skin2231-07702249-446410.4103/2231-0770.94806https://doaj.org/article/0cb62326d0574cfe9f331acaa469973c2012-01-01T00:00:00Zhttp://www.thieme-connect.de/DOI/DOI?10.4103/2231-0770.94806https://doaj.org/toc/2231-0770https://doaj.org/toc/2249-4464Esthesioneuroblastoma (ENB) is a rare tumor derived from olfactory neuroepithelium. ENB in a site outside of where olfactory epithelium exists is exceedingly rare with only five cases of ENB isolated to the sphenoid sinuses described in the literature to date. To the best of our knowledge, a skin metastasis of ENB outside the head and neck region has not been reported. We present an unusual case of a 33-year-old male diagnosed with primary sphenoid sinus ENB, who underwent surgical resection of the tumor followed by chemoradiation. About 5 months later, the patient developed a dermal mass in the sternal region, clinically suspicious for metastasis. Fine needle aspiration (FNA) revealed a tumor with morphological features and immunophenotype consistent with the metastasis from patient′s known primary sphenoid sinus ENB. Our case demonstrates that the skin may be a rare site of a metastatic ENB, and FNA is a cost-effective and reliable diagnostic method of a suspected cutaneous metastasis.Josephine AkinfolarinTarek JazaerlyKia JonesMaher Abu-HamdanFulvio LonardoAdam FolbeTamar GiorgadzeThieme Medical and Scientific Publishers Pvt. Ltd.articleesthesioneuroblastomametastasisskinMedicineRENAvicenna Journal of Medicine, Vol 02, Iss 01, Pp 15-18 (2012)
institution	DOAJ
collection	DOAJ
language	EN
topic	esthesioneuroblastoma metastasis skin Medicine R
spellingShingle	esthesioneuroblastoma metastasis skin Medicine R Josephine Akinfolarin Tarek Jazaerly Kia Jones Maher Abu-Hamdan Fulvio Lonardo Adam Folbe Tamar Giorgadze Fine needle aspiration cytology of primary sphenoid sinus esthesioneuroblastoma metastatic to the skin
description	Esthesioneuroblastoma (ENB) is a rare tumor derived from olfactory neuroepithelium. ENB in a site outside of where olfactory epithelium exists is exceedingly rare with only five cases of ENB isolated to the sphenoid sinuses described in the literature to date. To the best of our knowledge, a skin metastasis of ENB outside the head and neck region has not been reported. We present an unusual case of a 33-year-old male diagnosed with primary sphenoid sinus ENB, who underwent surgical resection of the tumor followed by chemoradiation. About 5 months later, the patient developed a dermal mass in the sternal region, clinically suspicious for metastasis. Fine needle aspiration (FNA) revealed a tumor with morphological features and immunophenotype consistent with the metastasis from patient′s known primary sphenoid sinus ENB. Our case demonstrates that the skin may be a rare site of a metastatic ENB, and FNA is a cost-effective and reliable diagnostic method of a suspected cutaneous metastasis.
format	article
author	Josephine Akinfolarin Tarek Jazaerly Kia Jones Maher Abu-Hamdan Fulvio Lonardo Adam Folbe Tamar Giorgadze
author_facet	Josephine Akinfolarin Tarek Jazaerly Kia Jones Maher Abu-Hamdan Fulvio Lonardo Adam Folbe Tamar Giorgadze
author_sort	Josephine Akinfolarin
title	Fine needle aspiration cytology of primary sphenoid sinus esthesioneuroblastoma metastatic to the skin
title_short	Fine needle aspiration cytology of primary sphenoid sinus esthesioneuroblastoma metastatic to the skin
title_full	Fine needle aspiration cytology of primary sphenoid sinus esthesioneuroblastoma metastatic to the skin
title_fullStr	Fine needle aspiration cytology of primary sphenoid sinus esthesioneuroblastoma metastatic to the skin
title_full_unstemmed	Fine needle aspiration cytology of primary sphenoid sinus esthesioneuroblastoma metastatic to the skin
title_sort	fine needle aspiration cytology of primary sphenoid sinus esthesioneuroblastoma metastatic to the skin
publisher	Thieme Medical and Scientific Publishers Pvt. Ltd.
publishDate	2012
url	https://doaj.org/article/0cb62326d0574cfe9f331acaa469973c
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Fine needle aspiration cytology of primary sphenoid sinus esthesioneuroblastoma metastatic to the skin

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