Pptc7 is an essential phosphatase for promoting mammalian mitochondrial metabolism and biogenesis

The mitochondria houses several phosphatases, but their function is not well characterized. Here, the authors show that mitochondrial phosphatase Pptc7 is important during development for proper mitochondrial function and has a role regulating protein import with the translocase subunit Timm50.

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Autores principales:	Natalie M. Niemi, Gary M. Wilson, Katherine A. Overmyer, F.-Nora Vögtle, Lisa Myketin, Danielle C. Lohman, Kathryn L. Schueler, Alan D. Attie, Chris Meisinger, Joshua J. Coon, David J. Pagliarini
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/0cc3120d036a46b9807f1cae4a084aeb
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spelling	oai:doaj.org-article:0cc3120d036a46b9807f1cae4a084aeb2021-12-02T16:58:13ZPptc7 is an essential phosphatase for promoting mammalian mitochondrial metabolism and biogenesis10.1038/s41467-019-11047-62041-1723https://doaj.org/article/0cc3120d036a46b9807f1cae4a084aeb2019-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-11047-6https://doaj.org/toc/2041-1723The mitochondria houses several phosphatases, but their function is not well characterized. Here, the authors show that mitochondrial phosphatase Pptc7 is important during development for proper mitochondrial function and has a role regulating protein import with the translocase subunit Timm50.Natalie M. NiemiGary M. WilsonKatherine A. OvermyerF.-Nora VögtleLisa MyketinDanielle C. LohmanKathryn L. SchuelerAlan D. AttieChris MeisingerJoshua J. CoonDavid J. PagliariniNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Natalie M. Niemi Gary M. Wilson Katherine A. Overmyer F.-Nora Vögtle Lisa Myketin Danielle C. Lohman Kathryn L. Schueler Alan D. Attie Chris Meisinger Joshua J. Coon David J. Pagliarini Pptc7 is an essential phosphatase for promoting mammalian mitochondrial metabolism and biogenesis
description	The mitochondria houses several phosphatases, but their function is not well characterized. Here, the authors show that mitochondrial phosphatase Pptc7 is important during development for proper mitochondrial function and has a role regulating protein import with the translocase subunit Timm50.
format	article
author	Natalie M. Niemi Gary M. Wilson Katherine A. Overmyer F.-Nora Vögtle Lisa Myketin Danielle C. Lohman Kathryn L. Schueler Alan D. Attie Chris Meisinger Joshua J. Coon David J. Pagliarini
author_facet	Natalie M. Niemi Gary M. Wilson Katherine A. Overmyer F.-Nora Vögtle Lisa Myketin Danielle C. Lohman Kathryn L. Schueler Alan D. Attie Chris Meisinger Joshua J. Coon David J. Pagliarini
author_sort	Natalie M. Niemi
title	Pptc7 is an essential phosphatase for promoting mammalian mitochondrial metabolism and biogenesis
title_short	Pptc7 is an essential phosphatase for promoting mammalian mitochondrial metabolism and biogenesis
title_full	Pptc7 is an essential phosphatase for promoting mammalian mitochondrial metabolism and biogenesis
title_fullStr	Pptc7 is an essential phosphatase for promoting mammalian mitochondrial metabolism and biogenesis
title_full_unstemmed	Pptc7 is an essential phosphatase for promoting mammalian mitochondrial metabolism and biogenesis
title_sort	pptc7 is an essential phosphatase for promoting mammalian mitochondrial metabolism and biogenesis
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/0cc3120d036a46b9807f1cae4a084aeb
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Pptc7 is an essential phosphatase for promoting mammalian mitochondrial metabolism and biogenesis

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