Rational construction of a reversible arylazo-based NIR probe for cycling hypoxia imaging in vivo
Most fluorescence probes to measure hypoxia are irreversible. Here, the authors develop a near infrared luminescent probe to measure hypoxia which is reversible and use the probe to monitor hypoxia-reoxygenation in several animal models.
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2021
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oai:doaj.org-article:0ccf6f7d1df7473296c3f3d99d745dfe2021-12-02T17:15:24ZRational construction of a reversible arylazo-based NIR probe for cycling hypoxia imaging in vivo10.1038/s41467-021-22855-02041-1723https://doaj.org/article/0ccf6f7d1df7473296c3f3d99d745dfe2021-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-22855-0https://doaj.org/toc/2041-1723Most fluorescence probes to measure hypoxia are irreversible. Here, the authors develop a near infrared luminescent probe to measure hypoxia which is reversible and use the probe to monitor hypoxia-reoxygenation in several animal models.Yuming ZhangWenxuan ZhaoYuncong ChenHao YuanHongbao FangShankun YaoChangli ZhangHongxia XuNan LiZhipeng LiuZijian GuoQingshun ZhaoYong LiangWeijiang HeNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-10 (2021) |
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Science Q Yuming Zhang Wenxuan Zhao Yuncong Chen Hao Yuan Hongbao Fang Shankun Yao Changli Zhang Hongxia Xu Nan Li Zhipeng Liu Zijian Guo Qingshun Zhao Yong Liang Weijiang He Rational construction of a reversible arylazo-based NIR probe for cycling hypoxia imaging in vivo |
description |
Most fluorescence probes to measure hypoxia are irreversible. Here, the authors develop a near infrared luminescent probe to measure hypoxia which is reversible and use the probe to monitor hypoxia-reoxygenation in several animal models. |
format |
article |
author |
Yuming Zhang Wenxuan Zhao Yuncong Chen Hao Yuan Hongbao Fang Shankun Yao Changli Zhang Hongxia Xu Nan Li Zhipeng Liu Zijian Guo Qingshun Zhao Yong Liang Weijiang He |
author_facet |
Yuming Zhang Wenxuan Zhao Yuncong Chen Hao Yuan Hongbao Fang Shankun Yao Changli Zhang Hongxia Xu Nan Li Zhipeng Liu Zijian Guo Qingshun Zhao Yong Liang Weijiang He |
author_sort |
Yuming Zhang |
title |
Rational construction of a reversible arylazo-based NIR probe for cycling hypoxia imaging in vivo |
title_short |
Rational construction of a reversible arylazo-based NIR probe for cycling hypoxia imaging in vivo |
title_full |
Rational construction of a reversible arylazo-based NIR probe for cycling hypoxia imaging in vivo |
title_fullStr |
Rational construction of a reversible arylazo-based NIR probe for cycling hypoxia imaging in vivo |
title_full_unstemmed |
Rational construction of a reversible arylazo-based NIR probe for cycling hypoxia imaging in vivo |
title_sort |
rational construction of a reversible arylazo-based nir probe for cycling hypoxia imaging in vivo |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/0ccf6f7d1df7473296c3f3d99d745dfe |
work_keys_str_mv |
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1718381243781873664 |