Rational construction of a reversible arylazo-based NIR probe for cycling hypoxia imaging in vivo

Rational construction of a reversible arylazo-based NIR probe for cycling hypoxia imaging in vivo

Most fluorescence probes to measure hypoxia are irreversible. Here, the authors develop a near infrared luminescent probe to measure hypoxia which is reversible and use the probe to monitor hypoxia-reoxygenation in several animal models.

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Autores principales: Yuming Zhang, Wenxuan Zhao, Yuncong Chen, Hao Yuan, Hongbao Fang, Shankun Yao, Changli Zhang, Hongxia Xu, Nan Li, Zhipeng Liu, Zijian Guo, Qingshun Zhao, Yong Liang, Weijiang He
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/0ccf6f7d1df7473296c3f3d99d745dfe
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spelling oai:doaj.org-article:0ccf6f7d1df7473296c3f3d99d745dfe2021-12-02T17:15:24ZRational construction of a reversible arylazo-based NIR probe for cycling hypoxia imaging in vivo10.1038/s41467-021-22855-02041-1723https://doaj.org/article/0ccf6f7d1df7473296c3f3d99d745dfe2021-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-22855-0https://doaj.org/toc/2041-1723Most fluorescence probes to measure hypoxia are irreversible. Here, the authors develop a near infrared luminescent probe to measure hypoxia which is reversible and use the probe to monitor hypoxia-reoxygenation in several animal models.Yuming ZhangWenxuan ZhaoYuncong ChenHao YuanHongbao FangShankun YaoChangli ZhangHongxia XuNan LiZhipeng LiuZijian GuoQingshun ZhaoYong LiangWeijiang HeNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Yuming Zhang
Wenxuan Zhao
Yuncong Chen
Hao Yuan
Hongbao Fang
Shankun Yao
Changli Zhang
Hongxia Xu
Nan Li
Zhipeng Liu
Zijian Guo
Qingshun Zhao
Yong Liang
Weijiang He
Rational construction of a reversible arylazo-based NIR probe for cycling hypoxia imaging in vivo
description Most fluorescence probes to measure hypoxia are irreversible. Here, the authors develop a near infrared luminescent probe to measure hypoxia which is reversible and use the probe to monitor hypoxia-reoxygenation in several animal models.
format article
author Yuming Zhang
Wenxuan Zhao
Yuncong Chen
Hao Yuan
Hongbao Fang
Shankun Yao
Changli Zhang
Hongxia Xu
Nan Li
Zhipeng Liu
Zijian Guo
Qingshun Zhao
Yong Liang
Weijiang He
author_facet Yuming Zhang
Wenxuan Zhao
Yuncong Chen
Hao Yuan
Hongbao Fang
Shankun Yao
Changli Zhang
Hongxia Xu
Nan Li
Zhipeng Liu
Zijian Guo
Qingshun Zhao
Yong Liang
Weijiang He
author_sort Yuming Zhang
title Rational construction of a reversible arylazo-based NIR probe for cycling hypoxia imaging in vivo
title_short Rational construction of a reversible arylazo-based NIR probe for cycling hypoxia imaging in vivo
title_full Rational construction of a reversible arylazo-based NIR probe for cycling hypoxia imaging in vivo
title_fullStr Rational construction of a reversible arylazo-based NIR probe for cycling hypoxia imaging in vivo
title_full_unstemmed Rational construction of a reversible arylazo-based NIR probe for cycling hypoxia imaging in vivo
title_sort rational construction of a reversible arylazo-based nir probe for cycling hypoxia imaging in vivo
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/0ccf6f7d1df7473296c3f3d99d745dfe
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