Influence of the Bioactive Diet Components on the Gene Expression Regulation

Diet bioactive components, in the concept of nutrigenetics and nutrigenomics, consist of food constituents, which can transfer information from the external environment and influence gene expression in the cell and thus the function of the whole organism. It is crucial to regard food not only as the...

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Autores principales:	Justyna Mierziak, Kamil Kostyn, Aleksandra Boba, Magdalena Czemplik, Anna Kulma, Wioleta Wojtasik
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	bioactive diet components gene expression DNA methylation histone modification non-coding RNA signalling cascades Nutrition. Foods and food supply TX341-641
Acceso en línea:	https://doaj.org/article/0cd5b87854b84495a25dc842e17e19ec
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spelling	oai:doaj.org-article:0cd5b87854b84495a25dc842e17e19ec2021-11-25T18:33:01ZInfluence of the Bioactive Diet Components on the Gene Expression Regulation10.3390/nu131136732072-6643https://doaj.org/article/0cd5b87854b84495a25dc842e17e19ec2021-10-01T00:00:00Zhttps://www.mdpi.com/2072-6643/13/11/3673https://doaj.org/toc/2072-6643Diet bioactive components, in the concept of nutrigenetics and nutrigenomics, consist of food constituents, which can transfer information from the external environment and influence gene expression in the cell and thus the function of the whole organism. It is crucial to regard food not only as the source of energy and basic nutriments, crucial for living and organism development, but also as the factor influencing health/disease, biochemical mechanisms, and activation of biochemical pathways. Bioactive components of the diet regulate gene expression through changes in the chromatin structure (including DNA methylation and histone modification), non-coding RNA, activation of transcription factors by signalling cascades, or direct ligand binding to the nuclear receptors. Analysis of interactions between diet components and human genome structure and gene activity is a modern approach that will help to better understand these relations and will allow designing dietary guidances, which can help maintain good health.Justyna MierziakKamil KostynAleksandra BobaMagdalena CzemplikAnna KulmaWioleta WojtasikMDPI AGarticlebioactive diet componentsgene expressionDNA methylationhistone modificationnon-coding RNAsignalling cascadesNutrition. Foods and food supplyTX341-641ENNutrients, Vol 13, Iss 3673, p 3673 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	bioactive diet components gene expression DNA methylation histone modification non-coding RNA signalling cascades Nutrition. Foods and food supply TX341-641
spellingShingle	bioactive diet components gene expression DNA methylation histone modification non-coding RNA signalling cascades Nutrition. Foods and food supply TX341-641 Justyna Mierziak Kamil Kostyn Aleksandra Boba Magdalena Czemplik Anna Kulma Wioleta Wojtasik Influence of the Bioactive Diet Components on the Gene Expression Regulation
description	Diet bioactive components, in the concept of nutrigenetics and nutrigenomics, consist of food constituents, which can transfer information from the external environment and influence gene expression in the cell and thus the function of the whole organism. It is crucial to regard food not only as the source of energy and basic nutriments, crucial for living and organism development, but also as the factor influencing health/disease, biochemical mechanisms, and activation of biochemical pathways. Bioactive components of the diet regulate gene expression through changes in the chromatin structure (including DNA methylation and histone modification), non-coding RNA, activation of transcription factors by signalling cascades, or direct ligand binding to the nuclear receptors. Analysis of interactions between diet components and human genome structure and gene activity is a modern approach that will help to better understand these relations and will allow designing dietary guidances, which can help maintain good health.
format	article
author	Justyna Mierziak Kamil Kostyn Aleksandra Boba Magdalena Czemplik Anna Kulma Wioleta Wojtasik
author_facet	Justyna Mierziak Kamil Kostyn Aleksandra Boba Magdalena Czemplik Anna Kulma Wioleta Wojtasik
author_sort	Justyna Mierziak
title	Influence of the Bioactive Diet Components on the Gene Expression Regulation
title_short	Influence of the Bioactive Diet Components on the Gene Expression Regulation
title_full	Influence of the Bioactive Diet Components on the Gene Expression Regulation
title_fullStr	Influence of the Bioactive Diet Components on the Gene Expression Regulation
title_full_unstemmed	Influence of the Bioactive Diet Components on the Gene Expression Regulation
title_sort	influence of the bioactive diet components on the gene expression regulation
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/0cd5b87854b84495a25dc842e17e19ec
work_keys_str_mv	AT justynamierziak influenceofthebioactivedietcomponentsonthegeneexpressionregulation AT kamilkostyn influenceofthebioactivedietcomponentsonthegeneexpressionregulation AT aleksandraboba influenceofthebioactivedietcomponentsonthegeneexpressionregulation AT magdalenaczemplik influenceofthebioactivedietcomponentsonthegeneexpressionregulation AT annakulma influenceofthebioactivedietcomponentsonthegeneexpressionregulation AT wioletawojtasik influenceofthebioactivedietcomponentsonthegeneexpressionregulation
_version_	1718410997871411200

Influence of the Bioactive Diet Components on the Gene Expression Regulation

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