Visual impairment in aging and cognitive decline: experience in a Memory Clinic

Abstract Visual impairment is common in people living with dementia and regular ophthalmological exams may improve their quality of life. We evaluated visual function in a cohort of elderly individuals and analyzed its association with their degree of cognitive impairment. Participants underwent neu...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Marta Marquié, Miguel Castilla-Martí, Sergi Valero, Joan Martínez, Domingo Sánchez, Isabel Hernández, Maitée Rosende-Roca, Liliana Vargas, Ana Mauleón, Octavio Rodríguez-Gómez, Carla Abdelnour, Silvia Gil, Miguel A. Santos-Santos, Montserrat Alegret, Ana Espinosa, Gemma Ortega, Alba Pérez-Cordón, Ángela Sanabria, Natalia Roberto, Sonia Moreno-Grau, Itziar de Rojas, Rafael Simó, Andreea Ciudin, Cristina Hernández, Adelina Orellana, Gemma Monté-Rubio, Alba Benaque, Agustín Ruiz, Lluís Tárraga, Mercè Boada
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/0ce0b1c095224ed481d85b588f61fae0
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:0ce0b1c095224ed481d85b588f61fae0
record_format	dspace
spelling	oai:doaj.org-article:0ce0b1c095224ed481d85b588f61fae02021-12-02T15:09:41ZVisual impairment in aging and cognitive decline: experience in a Memory Clinic10.1038/s41598-019-45055-92045-2322https://doaj.org/article/0ce0b1c095224ed481d85b588f61fae02019-06-01T00:00:00Zhttps://doi.org/10.1038/s41598-019-45055-9https://doaj.org/toc/2045-2322Abstract Visual impairment is common in people living with dementia and regular ophthalmological exams may improve their quality of life. We evaluated visual function in a cohort of elderly individuals and analyzed its association with their degree of cognitive impairment. Participants underwent neurological and neuropsychological exams, neuro-ophthalmological assessment (visual acuity, intraocular pressure, rates of past ophthalmological pathologies, use of ocular correction, treatments and surgeries) and optical coherence tomography (OCT) scan. We analyzed differences in ophthalmological characteristics among diagnostic groups. The final sample of 1746 study participants aged ≥ 50 comprised 229 individuals with Subjective Cognitive Decline (SCD), 695 with mild cognitive impairment (MCI) and 833 with Dementia (Alzheimer disease: n = 660; vascular dementia: n = 92, Lewy body dementia: n = 34; frontotemporal dementia: n = 19 and other: n = 28). Age, gender and education were used as covariates. Patients with Dementia, compared to those with SCD and MCI, presented worse visual acuity (p < 0.001), used less visual correction (p = 0.02 and p < 0.001, respectively) and fewer ophthalmological treatments (p = 0.004 and p < 0.001, respectively) and underwent fewer ocular surgeries (p = 0.009 and p < 0.001, respectively). OCT image quality worsened in parallel to cognitive decline (Dementia vs SCD: p = 0.008; Dementia vs MCI: p < 0.001). No group differences in past ophthalmological disorders or abnormal OCT findings were detected. Efforts should be made to ensure dementia patients undergo regular ophthalmological assessments to correct their visual function in order to improve their quality of life.Marta MarquiéMiguel Castilla-MartíSergi ValeroJoan MartínezDomingo SánchezIsabel HernándezMaitée Rosende-RocaLiliana VargasAna MauleónOctavio Rodríguez-GómezCarla AbdelnourSilvia GilMiguel A. Santos-SantosMontserrat AlegretAna EspinosaGemma OrtegaAlba Pérez-CordónÁngela SanabriaNatalia RobertoSonia Moreno-GrauItziar de RojasRafael SimóAndreea CiudinCristina HernándezAdelina OrellanaGemma Monté-RubioAlba BenaqueAgustín RuizLluís TárragaMercè BoadaNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Marta Marquié Miguel Castilla-Martí Sergi Valero Joan Martínez Domingo Sánchez Isabel Hernández Maitée Rosende-Roca Liliana Vargas Ana Mauleón Octavio Rodríguez-Gómez Carla Abdelnour Silvia Gil Miguel A. Santos-Santos Montserrat Alegret Ana Espinosa Gemma Ortega Alba Pérez-Cordón Ángela Sanabria Natalia Roberto Sonia Moreno-Grau Itziar de Rojas Rafael Simó Andreea Ciudin Cristina Hernández Adelina Orellana Gemma Monté-Rubio Alba Benaque Agustín Ruiz Lluís Tárraga Mercè Boada Visual impairment in aging and cognitive decline: experience in a Memory Clinic
description	Abstract Visual impairment is common in people living with dementia and regular ophthalmological exams may improve their quality of life. We evaluated visual function in a cohort of elderly individuals and analyzed its association with their degree of cognitive impairment. Participants underwent neurological and neuropsychological exams, neuro-ophthalmological assessment (visual acuity, intraocular pressure, rates of past ophthalmological pathologies, use of ocular correction, treatments and surgeries) and optical coherence tomography (OCT) scan. We analyzed differences in ophthalmological characteristics among diagnostic groups. The final sample of 1746 study participants aged ≥ 50 comprised 229 individuals with Subjective Cognitive Decline (SCD), 695 with mild cognitive impairment (MCI) and 833 with Dementia (Alzheimer disease: n = 660; vascular dementia: n = 92, Lewy body dementia: n = 34; frontotemporal dementia: n = 19 and other: n = 28). Age, gender and education were used as covariates. Patients with Dementia, compared to those with SCD and MCI, presented worse visual acuity (p < 0.001), used less visual correction (p = 0.02 and p < 0.001, respectively) and fewer ophthalmological treatments (p = 0.004 and p < 0.001, respectively) and underwent fewer ocular surgeries (p = 0.009 and p < 0.001, respectively). OCT image quality worsened in parallel to cognitive decline (Dementia vs SCD: p = 0.008; Dementia vs MCI: p < 0.001). No group differences in past ophthalmological disorders or abnormal OCT findings were detected. Efforts should be made to ensure dementia patients undergo regular ophthalmological assessments to correct their visual function in order to improve their quality of life.
format	article
author	Marta Marquié Miguel Castilla-Martí Sergi Valero Joan Martínez Domingo Sánchez Isabel Hernández Maitée Rosende-Roca Liliana Vargas Ana Mauleón Octavio Rodríguez-Gómez Carla Abdelnour Silvia Gil Miguel A. Santos-Santos Montserrat Alegret Ana Espinosa Gemma Ortega Alba Pérez-Cordón Ángela Sanabria Natalia Roberto Sonia Moreno-Grau Itziar de Rojas Rafael Simó Andreea Ciudin Cristina Hernández Adelina Orellana Gemma Monté-Rubio Alba Benaque Agustín Ruiz Lluís Tárraga Mercè Boada
author_facet	Marta Marquié Miguel Castilla-Martí Sergi Valero Joan Martínez Domingo Sánchez Isabel Hernández Maitée Rosende-Roca Liliana Vargas Ana Mauleón Octavio Rodríguez-Gómez Carla Abdelnour Silvia Gil Miguel A. Santos-Santos Montserrat Alegret Ana Espinosa Gemma Ortega Alba Pérez-Cordón Ángela Sanabria Natalia Roberto Sonia Moreno-Grau Itziar de Rojas Rafael Simó Andreea Ciudin Cristina Hernández Adelina Orellana Gemma Monté-Rubio Alba Benaque Agustín Ruiz Lluís Tárraga Mercè Boada
author_sort	Marta Marquié
title	Visual impairment in aging and cognitive decline: experience in a Memory Clinic
title_short	Visual impairment in aging and cognitive decline: experience in a Memory Clinic
title_full	Visual impairment in aging and cognitive decline: experience in a Memory Clinic
title_fullStr	Visual impairment in aging and cognitive decline: experience in a Memory Clinic
title_full_unstemmed	Visual impairment in aging and cognitive decline: experience in a Memory Clinic
title_sort	visual impairment in aging and cognitive decline: experience in a memory clinic
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/0ce0b1c095224ed481d85b588f61fae0
work_keys_str_mv	AT martamarquie visualimpairmentinagingandcognitivedeclineexperienceinamemoryclinic AT miguelcastillamarti visualimpairmentinagingandcognitivedeclineexperienceinamemoryclinic AT sergivalero visualimpairmentinagingandcognitivedeclineexperienceinamemoryclinic AT joanmartinez visualimpairmentinagingandcognitivedeclineexperienceinamemoryclinic AT domingosanchez visualimpairmentinagingandcognitivedeclineexperienceinamemoryclinic AT isabelhernandez visualimpairmentinagingandcognitivedeclineexperienceinamemoryclinic AT maiteerosenderoca visualimpairmentinagingandcognitivedeclineexperienceinamemoryclinic AT lilianavargas visualimpairmentinagingandcognitivedeclineexperienceinamemoryclinic AT anamauleon visualimpairmentinagingandcognitivedeclineexperienceinamemoryclinic AT octaviorodriguezgomez visualimpairmentinagingandcognitivedeclineexperienceinamemoryclinic AT carlaabdelnour visualimpairmentinagingandcognitivedeclineexperienceinamemoryclinic AT silviagil visualimpairmentinagingandcognitivedeclineexperienceinamemoryclinic AT miguelasantossantos visualimpairmentinagingandcognitivedeclineexperienceinamemoryclinic AT montserratalegret visualimpairmentinagingandcognitivedeclineexperienceinamemoryclinic AT anaespinosa visualimpairmentinagingandcognitivedeclineexperienceinamemoryclinic AT gemmaortega visualimpairmentinagingandcognitivedeclineexperienceinamemoryclinic AT albaperezcordon visualimpairmentinagingandcognitivedeclineexperienceinamemoryclinic AT angelasanabria visualimpairmentinagingandcognitivedeclineexperienceinamemoryclinic AT nataliaroberto visualimpairmentinagingandcognitivedeclineexperienceinamemoryclinic AT soniamorenograu visualimpairmentinagingandcognitivedeclineexperienceinamemoryclinic AT itziarderojas visualimpairmentinagingandcognitivedeclineexperienceinamemoryclinic AT rafaelsimo visualimpairmentinagingandcognitivedeclineexperienceinamemoryclinic AT andreeaciudin visualimpairmentinagingandcognitivedeclineexperienceinamemoryclinic AT cristinahernandez visualimpairmentinagingandcognitivedeclineexperienceinamemoryclinic AT adelinaorellana visualimpairmentinagingandcognitivedeclineexperienceinamemoryclinic AT gemmamonterubio visualimpairmentinagingandcognitivedeclineexperienceinamemoryclinic AT albabenaque visualimpairmentinagingandcognitivedeclineexperienceinamemoryclinic AT agustinruiz visualimpairmentinagingandcognitivedeclineexperienceinamemoryclinic AT lluistarraga visualimpairmentinagingandcognitivedeclineexperienceinamemoryclinic AT merceboada visualimpairmentinagingandcognitivedeclineexperienceinamemoryclinic
_version_	1718387734324707328

Visual impairment in aging and cognitive decline: experience in a Memory Clinic

Ejemplares similares