The effect of evening primrose oil on fatigue and quality of life in patients with multiple sclerosis

Nastaran Majdinasab,1 Foroogh Namjoyan,2 Mohsen Taghizadeh,3 Hamid Saki4 1Department of Neurology, Ahvaz Jundishapur University of Medical Sciences, Musculoskeletal Rehabilitation Research Center, Ahvaz, Iran; 2Department of Pharmacognosy, Marine Natural Pharmaceutical Research Center, School of Ph...

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Autores principales:	Majdinasab N, Namjoyan F, Taghizadeh M, Saki H
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2018
Materias:	Multiple sclerosis evening primrose oil placebo fatigue quality of life Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
Acceso en línea:	https://doaj.org/article/0ce38b4271db4d338fc9df1b25589433
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spelling	oai:doaj.org-article:0ce38b4271db4d338fc9df1b255894332021-12-02T03:54:11ZThe effect of evening primrose oil on fatigue and quality of life in patients with multiple sclerosis1178-2021https://doaj.org/article/0ce38b4271db4d338fc9df1b255894332018-06-01T00:00:00Zhttps://www.dovepress.com/the-effect-of-evening-primrose-oil-on-fatigue-and-quality-of-life-in-p-peer-reviewed-article-NDThttps://doaj.org/toc/1178-2021Nastaran Majdinasab,1 Foroogh Namjoyan,2 Mohsen Taghizadeh,3 Hamid Saki4 1Department of Neurology, Ahvaz Jundishapur University of Medical Sciences, Musculoskeletal Rehabilitation Research Center, Ahvaz, Iran; 2Department of Pharmacognosy, Marine Natural Pharmaceutical Research Center, School of Pharmacy, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran; 3Department of Nutrition, Research Center for Biochemistry & Nutrition in Metabolic Diseases, Kashan University of Medical Sciences, Kashan, Iran; 4Department of Neurology, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran Background: Multiple sclerosis (MS) is a chronic progressive and inflammatory disease of the central nervous system that is characterized by demyelination in the central nervous system. In regard to the prevalence of diseases and enormous costs imposed on society and the health system, finding a way to stop the progression of the disease using drugs with fewer side effects seems a serious sanitation issue to the health of the international community. This study aimed to evaluate the effect of evening primrose oil (EPO) on fatigue and quality of life in patients with MS.Materials and methods: In this double-blind randomized clinical trial, 52 patients with MS were chosen and categorized into 2 groups which received 2 doses of EPO and placebo. In addition, the quality of life and fatigue scale in these patients were investigated before the treatment and again 3 months after therapy. The findings were then compared between the 2 groups.Result: EPO consumption significantly increased cognitive function, vitality, and overall life satisfaction and also reduced pain and fatigue compared to placebo (P<0.05).Conclusion: Our findings indicated that EPO consumption had no impact on the quality of life in general; however, it had a significant effect on several important aspects of life quality such as the increase of cognitive function, vitality, and overall life satisfaction. It also reduced the pain and fatigue in comparison to the placebo consumption. Herbal medicines are brittle and have fewer side effects than chemical drugs. With use of this plant, reduced fatigue and improved quality of life were observed in MS patients. But the drug did not prevent the progression of the disease. Keywords: cognitive function, vitality, overall life satisfaction, pain, fatigue Majdinasab NNamjoyan FTaghizadeh MSaki HDove Medical PressarticleMultiple sclerosisevening primrose oilplacebofatiguequality of lifeNeurosciences. Biological psychiatry. NeuropsychiatryRC321-571Neurology. Diseases of the nervous systemRC346-429ENNeuropsychiatric Disease and Treatment, Vol Volume 14, Pp 1505-1512 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Multiple sclerosis evening primrose oil placebo fatigue quality of life Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
spellingShingle	Multiple sclerosis evening primrose oil placebo fatigue quality of life Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429 Majdinasab N Namjoyan F Taghizadeh M Saki H The effect of evening primrose oil on fatigue and quality of life in patients with multiple sclerosis
description	Nastaran Majdinasab,1 Foroogh Namjoyan,2 Mohsen Taghizadeh,3 Hamid Saki4 1Department of Neurology, Ahvaz Jundishapur University of Medical Sciences, Musculoskeletal Rehabilitation Research Center, Ahvaz, Iran; 2Department of Pharmacognosy, Marine Natural Pharmaceutical Research Center, School of Pharmacy, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran; 3Department of Nutrition, Research Center for Biochemistry & Nutrition in Metabolic Diseases, Kashan University of Medical Sciences, Kashan, Iran; 4Department of Neurology, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran Background: Multiple sclerosis (MS) is a chronic progressive and inflammatory disease of the central nervous system that is characterized by demyelination in the central nervous system. In regard to the prevalence of diseases and enormous costs imposed on society and the health system, finding a way to stop the progression of the disease using drugs with fewer side effects seems a serious sanitation issue to the health of the international community. This study aimed to evaluate the effect of evening primrose oil (EPO) on fatigue and quality of life in patients with MS.Materials and methods: In this double-blind randomized clinical trial, 52 patients with MS were chosen and categorized into 2 groups which received 2 doses of EPO and placebo. In addition, the quality of life and fatigue scale in these patients were investigated before the treatment and again 3 months after therapy. The findings were then compared between the 2 groups.Result: EPO consumption significantly increased cognitive function, vitality, and overall life satisfaction and also reduced pain and fatigue compared to placebo (P<0.05).Conclusion: Our findings indicated that EPO consumption had no impact on the quality of life in general; however, it had a significant effect on several important aspects of life quality such as the increase of cognitive function, vitality, and overall life satisfaction. It also reduced the pain and fatigue in comparison to the placebo consumption. Herbal medicines are brittle and have fewer side effects than chemical drugs. With use of this plant, reduced fatigue and improved quality of life were observed in MS patients. But the drug did not prevent the progression of the disease. Keywords: cognitive function, vitality, overall life satisfaction, pain, fatigue
format	article
author	Majdinasab N Namjoyan F Taghizadeh M Saki H
author_facet	Majdinasab N Namjoyan F Taghizadeh M Saki H
author_sort	Majdinasab N
title	The effect of evening primrose oil on fatigue and quality of life in patients with multiple sclerosis
title_short	The effect of evening primrose oil on fatigue and quality of life in patients with multiple sclerosis
title_full	The effect of evening primrose oil on fatigue and quality of life in patients with multiple sclerosis
title_fullStr	The effect of evening primrose oil on fatigue and quality of life in patients with multiple sclerosis
title_full_unstemmed	The effect of evening primrose oil on fatigue and quality of life in patients with multiple sclerosis
title_sort	effect of evening primrose oil on fatigue and quality of life in patients with multiple sclerosis
publisher	Dove Medical Press
publishDate	2018
url	https://doaj.org/article/0ce38b4271db4d338fc9df1b25589433
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The effect of evening primrose oil on fatigue and quality of life in patients with multiple sclerosis

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