Rosmarinus officinalis L. leaf extract improves Anxity impairment induced by tropane alkaloids extracted from Datura stramonium

The alkaloid extract of datura stramonium (rich of atropine, hyoscyamine, scopolamine) is used to evaluate its effect on the central nervous system in rats (locomotion, anxiety). The animals received the alkaloid extract of datura by intraperitoneal injection. However, after the injection a group of...

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Autores principales:	Didou Latifa, Azzaoui Fatima-Zahra, Ahami Ahmed omar touhami, Ed-Day Soumia, Kacimi Fatima Ezzahra, Boulbaroud Samira
Formato:	article
Lenguaje:	EN FR
Publicado:	EDP Sciences 2021
Materias:	Environmental sciences GE1-350
Acceso en línea:	https://doaj.org/article/0ce6acf8bd7542f490e4a568937941fd
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id	oai:doaj.org-article:0ce6acf8bd7542f490e4a568937941fd
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spelling	oai:doaj.org-article:0ce6acf8bd7542f490e4a568937941fd2021-11-12T11:44:08ZRosmarinus officinalis L. leaf extract improves Anxity impairment induced by tropane alkaloids extracted from Datura stramonium2267-124210.1051/e3sconf/202131901059https://doaj.org/article/0ce6acf8bd7542f490e4a568937941fd2021-01-01T00:00:00Zhttps://www.e3s-conferences.org/articles/e3sconf/pdf/2021/95/e3sconf_vigisan_01059.pdfhttps://doaj.org/toc/2267-1242The alkaloid extract of datura stramonium (rich of atropine, hyoscyamine, scopolamine) is used to evaluate its effect on the central nervous system in rats (locomotion, anxiety). The animals received the alkaloid extract of datura by intraperitoneal injection. However, after the injection a group of rats got an inhibitory treatment contain flavonoids extracted from Rosmarinus officinalis. At the dose of 50 mg/kg/body weight of the alkaloid extract, the female rats have shown a reduction of locomotor activity and an induction of an anxiogenic effect. In the other hand, the mixture of Datura stramonium and Rosmarinus officinalis showed a neuroprotective action with regard to the disorders induced by extracts of Datura stramonium.Didou LatifaAzzaoui Fatima-ZahraAhami Ahmed omar touhamiEd-Day SoumiaKacimi Fatima EzzahraBoulbaroud SamiraEDP SciencesarticleEnvironmental sciencesGE1-350ENFRE3S Web of Conferences, Vol 319, p 01059 (2021)
institution	DOAJ
collection	DOAJ
language	EN FR
topic	Environmental sciences GE1-350
spellingShingle	Environmental sciences GE1-350 Didou Latifa Azzaoui Fatima-Zahra Ahami Ahmed omar touhami Ed-Day Soumia Kacimi Fatima Ezzahra Boulbaroud Samira Rosmarinus officinalis L. leaf extract improves Anxity impairment induced by tropane alkaloids extracted from Datura stramonium
description	The alkaloid extract of datura stramonium (rich of atropine, hyoscyamine, scopolamine) is used to evaluate its effect on the central nervous system in rats (locomotion, anxiety). The animals received the alkaloid extract of datura by intraperitoneal injection. However, after the injection a group of rats got an inhibitory treatment contain flavonoids extracted from Rosmarinus officinalis. At the dose of 50 mg/kg/body weight of the alkaloid extract, the female rats have shown a reduction of locomotor activity and an induction of an anxiogenic effect. In the other hand, the mixture of Datura stramonium and Rosmarinus officinalis showed a neuroprotective action with regard to the disorders induced by extracts of Datura stramonium.
format	article
author	Didou Latifa Azzaoui Fatima-Zahra Ahami Ahmed omar touhami Ed-Day Soumia Kacimi Fatima Ezzahra Boulbaroud Samira
author_facet	Didou Latifa Azzaoui Fatima-Zahra Ahami Ahmed omar touhami Ed-Day Soumia Kacimi Fatima Ezzahra Boulbaroud Samira
author_sort	Didou Latifa
title	Rosmarinus officinalis L. leaf extract improves Anxity impairment induced by tropane alkaloids extracted from Datura stramonium
title_short	Rosmarinus officinalis L. leaf extract improves Anxity impairment induced by tropane alkaloids extracted from Datura stramonium
title_full	Rosmarinus officinalis L. leaf extract improves Anxity impairment induced by tropane alkaloids extracted from Datura stramonium
title_fullStr	Rosmarinus officinalis L. leaf extract improves Anxity impairment induced by tropane alkaloids extracted from Datura stramonium
title_full_unstemmed	Rosmarinus officinalis L. leaf extract improves Anxity impairment induced by tropane alkaloids extracted from Datura stramonium
title_sort	rosmarinus officinalis l. leaf extract improves anxity impairment induced by tropane alkaloids extracted from datura stramonium
publisher	EDP Sciences
publishDate	2021
url	https://doaj.org/article/0ce6acf8bd7542f490e4a568937941fd
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Rosmarinus officinalis L. leaf extract improves Anxity impairment induced by tropane alkaloids extracted from Datura stramonium

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