Transplantation of enteric nervous system stem cells rescues nitric oxide synthase deficient mouse colon

Isolated human and mouse enteric nervous system stem cells (ENSCs) are capable of integrating and promoting innervation of the mouse colon. Here the authors show that transplantation of mouse ENSCs into a mouse model of human enteric neuropathy restores colon motility.

Guardado en:

Detalles Bibliográficos
Autores principales:	Conor J. McCann, Julie E. Cooper, Dipa Natarajan, Benjamin Jevans, Laura E. Burnett, Alan J. Burns, Nikhil Thapar
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/0ceaa8fc20ed4bd89fa0da14270742fb
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:0ceaa8fc20ed4bd89fa0da14270742fb
record_format	dspace
spelling	oai:doaj.org-article:0ceaa8fc20ed4bd89fa0da14270742fb2021-12-02T15:38:43ZTransplantation of enteric nervous system stem cells rescues nitric oxide synthase deficient mouse colon10.1038/ncomms159372041-1723https://doaj.org/article/0ceaa8fc20ed4bd89fa0da14270742fb2017-07-01T00:00:00Zhttps://doi.org/10.1038/ncomms15937https://doaj.org/toc/2041-1723Isolated human and mouse enteric nervous system stem cells (ENSCs) are capable of integrating and promoting innervation of the mouse colon. Here the authors show that transplantation of mouse ENSCs into a mouse model of human enteric neuropathy restores colon motility.Conor J. McCannJulie E. CooperDipa NatarajanBenjamin JevansLaura E. BurnettAlan J. BurnsNikhil ThaparNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Conor J. McCann Julie E. Cooper Dipa Natarajan Benjamin Jevans Laura E. Burnett Alan J. Burns Nikhil Thapar Transplantation of enteric nervous system stem cells rescues nitric oxide synthase deficient mouse colon
description	Isolated human and mouse enteric nervous system stem cells (ENSCs) are capable of integrating and promoting innervation of the mouse colon. Here the authors show that transplantation of mouse ENSCs into a mouse model of human enteric neuropathy restores colon motility.
format	article
author	Conor J. McCann Julie E. Cooper Dipa Natarajan Benjamin Jevans Laura E. Burnett Alan J. Burns Nikhil Thapar
author_facet	Conor J. McCann Julie E. Cooper Dipa Natarajan Benjamin Jevans Laura E. Burnett Alan J. Burns Nikhil Thapar
author_sort	Conor J. McCann
title	Transplantation of enteric nervous system stem cells rescues nitric oxide synthase deficient mouse colon
title_short	Transplantation of enteric nervous system stem cells rescues nitric oxide synthase deficient mouse colon
title_full	Transplantation of enteric nervous system stem cells rescues nitric oxide synthase deficient mouse colon
title_fullStr	Transplantation of enteric nervous system stem cells rescues nitric oxide synthase deficient mouse colon
title_full_unstemmed	Transplantation of enteric nervous system stem cells rescues nitric oxide synthase deficient mouse colon
title_sort	transplantation of enteric nervous system stem cells rescues nitric oxide synthase deficient mouse colon
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/0ceaa8fc20ed4bd89fa0da14270742fb
work_keys_str_mv	AT conorjmccann transplantationofentericnervoussystemstemcellsrescuesnitricoxidesynthasedeficientmousecolon AT julieecooper transplantationofentericnervoussystemstemcellsrescuesnitricoxidesynthasedeficientmousecolon AT dipanatarajan transplantationofentericnervoussystemstemcellsrescuesnitricoxidesynthasedeficientmousecolon AT benjaminjevans transplantationofentericnervoussystemstemcellsrescuesnitricoxidesynthasedeficientmousecolon AT lauraeburnett transplantationofentericnervoussystemstemcellsrescuesnitricoxidesynthasedeficientmousecolon AT alanjburns transplantationofentericnervoussystemstemcellsrescuesnitricoxidesynthasedeficientmousecolon AT nikhilthapar transplantationofentericnervoussystemstemcellsrescuesnitricoxidesynthasedeficientmousecolon
_version_	1718386093063143424

Transplantation of enteric nervous system stem cells rescues nitric oxide synthase deficient mouse colon

Ejemplares similares