Molecular subtyping reveals immune alterations associated with progression of bronchial premalignant lesions
Bronchial premalignant lesions can potentially progress to lung squamous cell carcinoma. Here, the authors profile bronchial biopsies from high-risk smokers by RNA sequencing and identify four molecular subtypes of premalignant lesions and an immune molecular signature that associates with lesion pr...
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Autores principales: | Jennifer E. Beane, Sarah A. Mazzilli, Joshua D. Campbell, Grant Duclos, Kostyantyn Krysan, Christopher Moy, Catalina Perdomo, Michael Schaffer, Gang Liu, Sherry Zhang, Hanqiao Liu, Jessica Vick, Samjot S. Dhillon, Suso J. Platero, Steven M. Dubinett, Christopher Stevenson, Mary E. Reid, Marc E. Lenburg, Avrum E. Spira |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2019
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Materias: | |
Acceso en línea: | https://doaj.org/article/0cf5153a221648e9910fbb6ff4aaf085 |
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