Catalytic asymmetric reductive hydroalkylation of enamides and enecarbamates to chiral aliphatic amines
Enantiopure aliphatic amines are frequently encountered as chiral auxiliaries and synthetic intermediates for bioactive compounds. Here, the authors report a mild nickel-catalysed asymmetric reductive hydroalkylation to convert enamides and enecarbamates into α-branched chiral amines and derivatives...
Guardado en:
| Autores principales: | , , , , , , , |
|---|---|
| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
Nature Portfolio
2021
|
| Materias: | |
| Acceso en línea: | https://doaj.org/article/0cfb72108a7845349924ccda087c2aa8 |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
| Sumario: | Enantiopure aliphatic amines are frequently encountered as chiral auxiliaries and synthetic intermediates for bioactive compounds. Here, the authors report a mild nickel-catalysed asymmetric reductive hydroalkylation to convert enamides and enecarbamates into α-branched chiral amines and derivatives. |
|---|